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TNR

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GENERAL INFORMATION

Gene name

 TNR

Gene description

 Tenascin R

Protein class

 Predicted intracellular proteins
Predicted secreted proteins

Predicted localization

 Intracellular,Secreted

Number of transcripts

 3
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Cell line enhanced (SH-SY5Y, U-937)

Protein evidence

 Evidence at protein level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
AF22SH-SY5YU-138 MGU-251 MGU-87 MGA-431HaCaTSK-MEL-30WM-115HELHL-60HMC-1K-562NB-4THP-1U-937DaudiHDLM-2Karpas-707MOLT-4REHRPMI-8226U-266/70U-266/84U-698A549SCLC-21HCACO-2CAPAN-2Hep G2AN3-CAEFO-21HeLaMCF7SiHaSK-BR-3T-47dHEK 293NTERA-2PC-3RPTEC TERT1RT4ASC TERT1LHCN-M2RH-30U-2 OSU-2197BJBJ hTERT+BJ hTERT+ SV40 Large T+BJ hTERT+ SV40 Large T+ RasG12VHBF TERT88HUVEC TERT2TIMEBEWOhTCEpi0246810
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (SH-SY5Y, U-937)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.
AF22SH-SY5YU-138 MGU-251 MGU-87 MGA-431HaCaTSK-MEL-30WM-115HELHL-60HMC-1K-562NB-4THP-1U-937DaudiHDLM-2Karpas-707MOLT-4REHRPMI-8226U-266/70U-266/84U-698A549SCLC-21HCACO-2CAPAN-2Hep G2AN3-CAEFO-21HeLaMCF7SiHaSK-BR-3T-47dHEK 293NTERA-2PC-3RPTEC TERT1RT4ASC TERT1LHCN-M2RH-30U-2 OSU-2197BJBJ hTERT+BJ hTERT+ SV40 Large T+BJ hTERT+ SV40 Large T+ RasG12VHBF TERT88HUVEC TERT2TIMEBEWOhTCEpi0246810TPMBrainSkinMyeloidLymphoidLungAbdominalBreast, female reproductive systemRenal, urinary, male reproductive systemSarcomaFibroblastEndothelialMiscellaneous

GENE INFORMATION

Gene name

 TNR

Synonyms

Description

 Tenascin R (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The encoded protein is restricted to the central nervous system. The protein may play a role in neurite outgrowth, neural cell adhesion and modulation of sodium channel function. It is a constituent of perineuronal nets. [provided by RefSeq, Aug 2013]

Chromosome

 1

Cytoband

 q25.1

Chromosome location (bp)

 175315194 - 175743770

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000116147 (version 83.38)

Entrez gene

 7143

UniProt

 Q92752 (UniProt - Evidence at protein level)

neXtProt

 NX_Q92752

Antibodypedia

 TNR antibodies

PROTEIN BROWSER
TNR-001
TNR-002
TNR-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TNR-001
ENSP00000356646
ENST00000367674
Q92752 [Direct mapping]
Tenascin-R
Show all
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SCAMPI predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0005578 [proteinaceous extracellular matrix]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0007155 [cell adhesion]
GO:0007158 [neuron cell-cell adhesion]
GO:0007411 [axon guidance]
GO:0008306 [associative learning]
GO:0009986 [cell surface]
GO:0010977 [negative regulation of neuron projection development]
GO:0022029 [telencephalon cell migration]
GO:0022408 [negative regulation of cell-cell adhesion]
GO:0030198 [extracellular matrix organization]
GO:0030517 [negative regulation of axon extension]
GO:0035641 [locomotory exploration behavior]
GO:0045121 [membrane raft]
GO:0048692 [negative regulation of axon extension involved in regeneration]
GO:0050804 [modulation of synaptic transmission]
GO:0050805 [negative regulation of synaptic transmission]
GO:0050808 [synapse organization]
GO:0050885 [neuromuscular process controlling balance]
GO:0051968 [positive regulation of synaptic transmission, glutamatergic]
GO:0051971 [positive regulation of transmission of nerve impulse]
GO:0060291 [long-term synaptic potentiation]
GO:0072534 [perineuronal net]
Show all
 1358 aa
149.6 kDa 		Yes 0
TNR-002
ENSP00000403413
ENST00000422274
H0Y668 [Direct mapping]
Tenascin-R
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
 181 aa
19.8 kDa 		No 0
TNR-201
ENSP00000263525
ENST00000263525
Q92752 [Direct mapping]
Tenascin-R
Show all
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SCAMPI predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0005578 [proteinaceous extracellular matrix]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0007155 [cell adhesion]
GO:0007411 [axon guidance]
GO:0030198 [extracellular matrix organization]
Show all
 1358 aa
149.6 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.