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SLC35D1

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GENERAL INFORMATION

Gene name

 SLC35D1

Gene description

 Solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1

Protein class

 Disease related genes
Potential drug targets
Predicted membrane proteins
Transporters

Predicted localization

 Membrane

Number of transcripts

 1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Expressed in all

Protein evidence

 Evidence at protein level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 SLC35D1 (HGNC Symbol)

Synonyms

 KIAA0260, UGTREL7

Description

 Solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 (HGNC Symbol)

Entrez gene summary

 Glycosylation of cellular glycoconjugates occurs in the endoplasmic reticulum (ER) and Golgi compartment, and requires transport of nucleotide sugars from the cytosol into the lumen of the ER and Golgi by specific transporters. The protein encoded by this gene resides in the ER, and transports both UDP-glucuronic acid (UDP-GlcA) and UDP-N-acetylgalactosamine (UDP-GalNAc) from the cytoplasm to the ER lumen. It may participate in glucuronidation and/or chondroitin sulfate biosynthesis. Mutations in this gene are associated with Schneckenbecken dysplasia.[provided by RefSeq, Sep 2009]

Chromosome

 1

Cytoband

 p31.3

Chromosome location (bp)

 66999332 - 67054099

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000116704 (version 83.38)

Entrez gene

 23169

UniProt

 Q9NTN3 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9NTN3

Antibodypedia

 SLC35D1 antibodies

PROTEIN BROWSER
SLC35D1-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SLC35D1-001
ENSP00000235345
ENST00000235345
Q9NTN3 [Direct mapping]
UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter
Show all
Transporters
   Electrochemical Potential-driven transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   >9TM proteins predicted by MDM
Disease related genes
Potential drug targets
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005461 [UDP-glucuronic acid transmembrane transporter activity]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0006065 [UDP-glucuronate biosynthetic process]
GO:0006805 [xenobiotic metabolic process]
GO:0008643 [carbohydrate transport]
GO:0015165 [pyrimidine nucleotide-sugar transmembrane transporter activity]
GO:0015297 [antiporter activity]
GO:0015781 [pyrimidine nucleotide-sugar transport]
GO:0015787 [UDP-glucuronic acid transport]
GO:0016021 [integral component of membrane]
GO:0030206 [chondroitin sulfate biosynthetic process]
GO:0044281 [small molecule metabolic process]
GO:0048706 [embryonic skeletal system development]
GO:0052695 [cellular glucuronidation]
GO:0055085 [transmembrane transport]
GO:0090481 [pyrimidine nucleotide-sugar transmembrane transport]
GO:0098656 [anion transmembrane transport]
Show all
 355 aa
39.2 kDa 		No >9

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.