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HAO2

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GENERAL INFORMATION

Gene name

 HAO2

Gene description

 Hydroxyacid oxidase 2 (long chain)

Protein class

 Enzymes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 4
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Not detected

Protein evidence

 Evidence at protein level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 HAO2 (HGNC Symbol)

Synonyms

 GIG16, HAOX2

Description

 Hydroxyacid oxidase 2 (long chain) (HGNC Symbol)

Entrez gene summary

 This gene is one of three related genes that have 2-hydroxyacid oxidase activity. The encoded protein localizes to the peroxisome has the highest activity toward the substrate 2-hydroxypalmitate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

Chromosome

 1

Cytoband

 p12

Chromosome location (bp)

 119368779 - 119394130

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000116882 (version 83.38)

Entrez gene

 51179

UniProt

 Q9NYQ3 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9NYQ3

Antibodypedia

 HAO2 antibodies

PROTEIN BROWSER
HAO2-001
HAO2-002
HAO2-003
HAO2-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
HAO2-001
ENSP00000354314
ENST00000361035
Q9NYQ3 [Direct mapping]
Hydroxyacid oxidase 2
Show all
Enzymes
   ENZYME proteins
   Oxidoreductases
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003973 [(S)-2-hydroxy-acid oxidase activity]
GO:0005102 [receptor binding]
GO:0005739 [mitochondrion]
GO:0005777 [peroxisome]
GO:0010181 [FMN binding]
GO:0016491 [oxidoreductase activity]
GO:0019395 [fatty acid oxidation]
GO:0052852 [very-long-chain-(S)-2-hydroxy-acid oxidase activity]
GO:0052853 [long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity]
GO:0052854 [medium-chain-(S)-2-hydroxy-acid oxidase activity]
GO:0055114 [oxidation-reduction process]
GO:0070062 [extracellular exosome]
Show all
 364 aa
40.4 kDa 		No 0
HAO2-002
ENSP00000316339
ENST00000325945
Q9NYQ3 [Direct mapping]
Hydroxyacid oxidase 2
Show all
Enzymes
   ENZYME proteins
   Oxidoreductases
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003973 [(S)-2-hydroxy-acid oxidase activity]
GO:0005102 [receptor binding]
GO:0005777 [peroxisome]
GO:0010181 [FMN binding]
GO:0016491 [oxidoreductase activity]
GO:0019395 [fatty acid oxidation]
GO:0052852 [very-long-chain-(S)-2-hydroxy-acid oxidase activity]
GO:0052853 [long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity]
GO:0052854 [medium-chain-(S)-2-hydroxy-acid oxidase activity]
GO:0055114 [oxidation-reduction process]
GO:0070062 [extracellular exosome]
Show all
 351 aa
38.8 kDa 		No 0
HAO2-003
ENSP00000393955
ENST00000457318
Q5QP02 [Direct mapping]
Hydroxyacid oxidase 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0010181 [FMN binding]
GO:0016491 [oxidoreductase activity]
GO:0055114 [oxidation-reduction process]
Show all
 186 aa
21.3 kDa 		No 0
HAO2-201
ENSP00000483507
ENST00000622548
Q9NYQ3 [Direct mapping]
Hydroxyacid oxidase 2
Show all
Enzymes
   ENZYME proteins
   Oxidoreductases
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003973 [(S)-2-hydroxy-acid oxidase activity]
GO:0005102 [receptor binding]
GO:0005777 [peroxisome]
GO:0010181 [FMN binding]
GO:0016491 [oxidoreductase activity]
GO:0019395 [fatty acid oxidation]
GO:0052852 [very-long-chain-(S)-2-hydroxy-acid oxidase activity]
GO:0052853 [long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity]
GO:0052854 [medium-chain-(S)-2-hydroxy-acid oxidase activity]
GO:0055114 [oxidation-reduction process]
GO:0070062 [extracellular exosome]
Show all
 351 aa
38.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.