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RRAGC

GENERAL INFORMATION

Gene name

 RRAGC

Gene description

 Ras-related GTP binding C

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 General nuclear expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Supported based on 1 antibody.
HPA018247
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 RRAGC (HGNC Symbol)

Synonyms

 FLJ13311, GTR2

Description

 Ras-related GTP binding C (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the GTR/RAG GTP-binding protein family. The encoded protein is a monomeric guanine nucleotide-binding protein which forms a heterodimer with RRAGA and RRAGB and is primarily localized to the cytoplasm. The encoded protein promotes intracellular localization of the mTOR complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]

Chromosome

 1

Cytoband

 p34.3

Chromosome location (bp)

 38838198 - 38859823

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000116954 (version 83.38)

Entrez gene

 64121

UniProt

 Q9HB90 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9HB90

Antibodypedia

 RRAGC antibodies

PROTEIN BROWSER
RRAGC-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RRAGC-001
ENSP00000362092
ENST00000373001
Q9HB90 [Direct mapping]
Ras-related GTP-binding protein C
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000287 [magnesium ion binding]
GO:0003924 [GTPase activity]
GO:0005515 [protein binding]
GO:0005525 [GTP binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005764 [lysosome]
GO:0005829 [cytosol]
GO:0006351 [transcription, DNA-templated]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0006915 [apoptotic process]
GO:0007050 [cell cycle arrest]
GO:0007264 [small GTPase mediated signal transduction]
GO:0008286 [insulin receptor signaling pathway]
GO:0008380 [RNA splicing]
GO:0009267 [cellular response to starvation]
GO:0010467 [gene expression]
GO:0010506 [regulation of autophagy]
GO:0016049 [cell growth]
GO:0016236 [macroautophagy]
GO:0019003 [GDP binding]
GO:0032006 [regulation of TOR signaling]
GO:0032008 [positive regulation of TOR signaling]
GO:0034198 [cellular response to amino acid starvation]
GO:0034448 [EGO complex]
GO:0034613 [cellular protein localization]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0046982 [protein heterodimerization activity]
GO:0071230 [cellular response to amino acid stimulus]
GO:1990131 [Gtr1-Gtr2 GTPase complex]
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 399 aa
44.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.