Expression of NT5C1A in cancer - Summary

CANCER ATLAS

Gene description

5'-nucleotidase, cytosolic IA

Protein class

Enzymes, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA050283	HPA054158

GENE INFORMATION
Gene name	NT5C1A (HGNC Symbol)
Synonyms	CN-I, CN-IA, CN1, CN1A, MGC119199, MGC119201
Description	5'-nucleotidase, cytosolic IA (HGNC Symbol)
Entrez gene summary	Cytosolic nucleotidases, such as NT5C1A, dephosphorylate nucleoside monophosphates (Hunsucker et al., 2001 [PubMed 11133996]).[supplied by OMIM, Mar 2008]
Chromosome	1
Cytoband	p34.2
Chromosome location (bp)	39659121 - 39672038
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000116981 (version 83.38)
Entrez gene	84618
UniProt	Q9BXI3 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9BXI3
Antibodypedia	NT5C1A antibodies

PROTEIN BROWSER

NT5C1A-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NT5C1A-001 ENSP00000235628 ENST00000235628	Q9BXI3 [Direct mapping] Cytosolic 5'-nucleotidase 1A Show all	Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0000287 [magnesium ion binding] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0006144 [purine nucleobase metabolic process] GO:0006195 [purine nucleotide catabolic process] GO:0006206 [pyrimidine nucleobase metabolic process] GO:0008253 [5'-nucleotidase activity] GO:0009116 [nucleoside metabolic process] GO:0009117 [nucleotide metabolic process] GO:0009128 [purine nucleoside monophosphate catabolic process] GO:0016311 [dephosphorylation] GO:0044281 [small molecule metabolic process] GO:0046085 [adenosine metabolic process] GO:0046135 [pyrimidine nucleoside catabolic process] GO:0055086 [nucleobase-containing small molecule metabolic process] Show all	368 aa 41 kDa	No	0