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CDK18

CANCER ATLAS

Gene description

 Cyclin-dependent kinase 18

Protein class

 Enzymes, Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA045429

GENE INFORMATION

Gene name

 CDK18 (HGNC Symbol)

Synonyms

 PCTAIRE3, PCTK3

Description

 Cyclin-dependent kinase 18 (HGNC Symbol)

Entrez gene summary

Chromosome

 1

Cytoband

 q32.1

Chromosome location (bp)

 205504595 - 205532793

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000117266 (version 83.38)

Entrez gene

 5129

UniProt

 Q07002 (UniProt - Evidence at protein level)

neXtProt

 NX_Q07002

Antibodypedia

 CDK18 antibodies

PROTEIN BROWSER
CDK18-001
CDK18-003
CDK18-005
CDK18-006
CDK18-007
CDK18-015
CDK18-019

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CDK18-001
ENSP00000353176
ENST00000360066
Q07002 [Direct mapping]
Cyclin-dependent kinase 18
A0A024R996 [Target identity:100%; Query identity:100%]
PCTAIRE protein kinase 3, isoform CRA_b
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   CMGC Ser/Thr protein kinases
   MEMSAT-SVM predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0004693 [cyclin-dependent protein serine/threonine kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005575 [cellular_component]
GO:0006468 [protein phosphorylation]
GO:0051726 [regulation of cell cycle]
Show all
 474 aa
54.4 kDa 		No 0
CDK18-003
ENSP00000399082
ENST00000429964
Q07002 [Direct mapping]
Cyclin-dependent kinase 18
A0A024R996 [Target identity:100%; Query identity:100%]
PCTAIRE protein kinase 3, isoform CRA_b
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   CMGC Ser/Thr protein kinases
   MEMSAT-SVM predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0004693 [cyclin-dependent protein serine/threonine kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005575 [cellular_component]
GO:0006468 [protein phosphorylation]
GO:0051726 [regulation of cell cycle]
Show all
 474 aa
54.4 kDa 		No 0
CDK18-005
ENSP00000423408
ENST00000478560
D6RA44 [Direct mapping]
Cyclin-dependent kinase 18
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0005524 [ATP binding]
GO:0006468 [protein phosphorylation]
Show all
 180 aa
20.8 kDa 		No 0
CDK18-006
ENSP00000423665
ENST00000506784
Q07002 [Direct mapping]
Cyclin-dependent kinase 18
A0A024R980 [Target identity:100%; Query identity:100%]
PCTAIRE protein kinase 3, isoform CRA_a
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   CMGC Ser/Thr protein kinases
   MEMSAT-SVM predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0004693 [cyclin-dependent protein serine/threonine kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005575 [cellular_component]
GO:0006468 [protein phosphorylation]
GO:0051726 [regulation of cell cycle]
Show all
 504 aa
57.6 kDa 		No 0
CDK18-007
ENSP00000391324
ENST00000419301
A0A0A0MSJ6 [Direct mapping]
Cyclin-dependent kinase 18
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0005524 [ATP binding]
GO:0006468 [protein phosphorylation]
Show all
 284 aa
32.5 kDa 		No 0
CDK18-015
ENSP00000426368
ENST00000506215
D6RGH0 [Direct mapping]
Cyclin-dependent kinase 18
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 65 aa
7.3 kDa 		No 0
CDK18-019
ENSP00000397831
ENST00000443813
D6R9B0 [Direct mapping]
Cyclin-dependent kinase 18
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 159 aa
18.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.