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Several cases of skin and colorectal cancer, head and neck cancers along with few cases of lung cancers showed weak to moderate membranous and cytoplasmic staining. Few cases of prostate and testis cancers displayed weak to moderate nucleolar and cytoplasmic positivity. Remaining cancer tissues were weakly stained or negative.
GENE INFORMATION
Gene name
IPO13 (HGNC Symbol)
Synonyms
IMP13, KIAA0724, RANBP13
Description
Importin 13 (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the importin-beta family of nuclear transport proteins. The encoded protein mediates the import of specific cargo proteins from the cytoplasm to the nucleus and is dependent on the Ras-related nuclear protein-GTPase system. The encoded protein is also involved in nuclear export of the eukaryotic translation initiation factor 1A.[provided by RefSeq, Mar 2009]
Transporters Transporter channels and pores THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)