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IPO13

GENERAL INFORMATION

Gene name

 IPO13

Gene description

 Importin 13

Protein class

 Predicted intracellular proteins
Transporters

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in most tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data.

Reliability score

 Uncertain based on 1 antibody.
CAB070425
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 IPO13 (HGNC Symbol)

Synonyms

 IMP13, KIAA0724, RANBP13

Description

 Importin 13 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the importin-beta family of nuclear transport proteins. The encoded protein mediates the import of specific cargo proteins from the cytoplasm to the nucleus and is dependent on the Ras-related nuclear protein-GTPase system. The encoded protein is also involved in nuclear export of the eukaryotic translation initiation factor 1A.[provided by RefSeq, Mar 2009]

Chromosome

 1

Cytoband

 p34.1

Chromosome location (bp)

 43946939 - 43968022

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000117408 (version 83.38)

Entrez gene

 9670

UniProt

 O94829 (UniProt - Evidence at protein level)

neXtProt

 NX_O94829

Antibodypedia

 IPO13 antibodies

PROTEIN BROWSER
IPO13-001
IPO13-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
IPO13-001
ENSP00000361418
ENST00000372343
O94829 [Direct mapping]
Importin-13
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Transporters
   Transporter channels and pores
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0006606 [protein import into nucleus]
GO:0006886 [intracellular protein transport]
GO:0008139 [nuclear localization sequence binding]
GO:0008536 [Ran GTPase binding]
GO:0008565 [protein transporter activity]
GO:0031965 [nuclear membrane]
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 963 aa
108.2 kDa 		No 0
IPO13-002
ENSP00000361414
ENST00000372339
Q5T4X2 [Direct mapping]
Importin-13; cDNA FLJ34246 fis, clone FCBBF4000061, highly similar to Importin-13
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 181 aa
20.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.