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CNN3

CANCER ATLAS

Gene description

 Calponin 3, acidic

Protein class

 Plasma proteins, Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA051237
CAB009849

GENE INFORMATION

Gene name

 CNN3

Synonyms

Description

 Calponin 3, acidic (HGNC Symbol)

Entrez gene summary

 This gene encodes a protein with a markedly acidic C terminus; the basic N-terminus is highly homologous to the N-terminus of a related gene, CNN1. Members of the CNN gene family all contain similar tandemly repeated motifs. This encoded protein is associated with the cytoskeleton but is not involved in contraction. [provided by RefSeq, Jul 2008]

Chromosome

 1

Cytoband

 p21.3

Chromosome location (bp)

 94896949 - 94927278

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000117519 (version 83.38)

Entrez gene

 1266

UniProt

 Q15417 (UniProt - Evidence at protein level)

neXtProt

 NX_Q15417

Antibodypedia

 CNN3 antibodies

PROTEIN BROWSER
CNN3-001
CNN3-002
CNN3-201
CNN3-202

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CNN3-001
ENSP00000359225
ENST00000370206
Q15417 [Direct mapping]
Calponin-3
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003779 [actin binding]
GO:0005515 [protein binding]
GO:0005516 [calmodulin binding]
GO:0005737 [cytoplasm]
GO:0005925 [focal adhesion]
GO:0008017 [microtubule binding]
GO:0014069 [postsynaptic density]
GO:0015629 [actin cytoskeleton]
GO:0030425 [dendrite]
GO:0030855 [epithelial cell differentiation]
GO:0031032 [actomyosin structure organization]
GO:0032780 [negative regulation of ATPase activity]
GO:0043025 [neuronal cell body]
GO:0043197 [dendritic spine]
Show all
 329 aa
36.4 kDa 		No 0
CNN3-002
ENSP00000401452
ENST00000415017
E9PDU6 [Direct mapping]
Calponin
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003779 [actin binding]
GO:0005515 [protein binding]
GO:0005516 [calmodulin binding]
GO:0031032 [actomyosin structure organization]
Show all
 185 aa
20.2 kDa 		No 0
CNN3-201
ENSP00000377752
ENST00000394202
Q15417 [Direct mapping]
Calponin-3
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003779 [actin binding]
GO:0005515 [protein binding]
GO:0005516 [calmodulin binding]
GO:0005737 [cytoplasm]
GO:0005925 [focal adhesion]
GO:0015629 [actin cytoskeleton]
GO:0030855 [epithelial cell differentiation]
GO:0031032 [actomyosin structure organization]
Show all
 283 aa
31.4 kDa 		No 0
CNN3-202
ENSP00000440081
ENST00000545882
Q15417 [Direct mapping]
Calponin-3
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003779 [actin binding]
GO:0005515 [protein binding]
GO:0005516 [calmodulin binding]
GO:0005737 [cytoplasm]
GO:0005925 [focal adhesion]
GO:0015629 [actin cytoskeleton]
GO:0030855 [epithelial cell differentiation]
GO:0031032 [actomyosin structure organization]
Show all
 288 aa
31.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.