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TNP1

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GENERAL INFORMATION

Gene name

 TNP1

Gene description

 Transition protein 1 (during histone to protamine replacement)

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Cell line enhanced (Hep G2, U-2197)

Protein evidence

 Evidence at protein level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (Hep G2, U-2197)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 TNP1

Synonyms

Description

 Transition protein 1 (during histone to protamine replacement) (HGNC Symbol)

Entrez gene summary

 Transition protein-1 is a spermatid-specific product of the haploid genome which replaces histone and is itself replaced in the mature sperm by the protamines (see PRM1, MIM 182880; PRM2, MIM 182890) (Luerssen et al., 1990 [PubMed 2249851]).[supplied by OMIM, Mar 2008]

Chromosome

 2

Cytoband

 q35

Chromosome location (bp)

 216859458 - 216860064

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000118245 (version 83.38)

Entrez gene

 7141

UniProt

 P09430 (UniProt - Evidence at protein level)

neXtProt

 NX_P09430

Antibodypedia

 TNP1 antibodies

PROTEIN BROWSER
TNP1-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TNP1-001
ENSP00000236979
ENST00000236979
P09430 [Direct mapping]
Spermatid nuclear transition protein 1
Q4ZG82 [Target identity:100%; Query identity:100%]
Putative uncharacterized protein TNP1; Transition protein 1; Transition protein 1 (During histone to protamine replacement)
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Predicted intracellular proteins
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GO:0000012 [single strand break repair]
GO:0000786 [nucleosome]
GO:0001673 [male germ cell nucleus]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0006337 [nucleosome disassembly]
GO:0006338 [chromatin remodeling]
GO:0006342 [chromatin silencing]
GO:0007275 [multicellular organismal development]
GO:0007283 [spermatogenesis]
GO:0007286 [spermatid development]
GO:0007289 [spermatid nucleus differentiation]
GO:0007290 [spermatid nucleus elongation]
GO:0019953 [sexual reproduction]
GO:0030317 [sperm motility]
GO:0035042 [fertilization, exchange of chromosomal proteins]
GO:0045892 [negative regulation of transcription, DNA-templated]
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 55 aa
6.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.