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Few cases of renal cancers showed weak cytoplasmic staining. Remaining cancer tissues were generally negative.
GENE INFORMATION
Gene name
ONECUT2 (HGNC Symbol)
Synonyms
OC-2
Description
One cut homeobox 2 (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the onecut family of transcription factors, which are characterized by a cut domain and an atypical homeodomain. The protein binds to specific DNA sequences and stimulates expression of target genes, including genes involved in melanocyte and hepatocyte differentiation. [provided by RefSeq, Jul 2008]