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Most cancer cells showed weak to moderate nucleolar staining with additional cytoplasmic positivity in several cases. Several cases of gliomas, lymphomas, carcinoids and renal cell carcinomas were negative.
SUPT7L is a protein subunit of the human STAGA complex (SPT3; (MIM 602947)/TAF9 (MIM 600822)/GCN5 (MIM 602301) acetyltransferase complex), which is a chromatin-modifying multiprotein complex (Martinez et al., 2001 [PubMed 11564863]).[supplied by OMIM, Apr 2009]