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SUPT7L

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GENERAL INFORMATION

Gene name

 SUPT7L

Gene description

 SPT7-like STAGA complex gamma subunit

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 5
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HUMAN PROTEIN ATLAS INFORMATION

Summary

 Localized to the nucleoplasm.

RNA cell category

 Expressed in all

Protein evidence

 Evidence at protein level

Main location

 Localized to the Nucleoplasm (approved)

DATA RELIABILITY

Reliability score

 Approved based on 1 antibody.
HPA063643
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ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Localized to the nucleoplasm.

Main location

 Nucleoplasm (approved)

 

 

 
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Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA063643 RH-30 No staining    
HPA063643 SH-SY5Y Nucleoplasm
HPA063643 U-2 OS No staining    

GENE INFORMATION

Gene name

 SUPT7L (HGNC Symbol)

Synonyms

 KIAA0764, SPT7L, STAF65, STAF65gamma

Description

 SPT7-like STAGA complex gamma subunit (HGNC Symbol)

Entrez gene summary

 SUPT7L is a protein subunit of the human STAGA complex (SPT3; (MIM 602947)/TAF9 (MIM 600822)/GCN5 (MIM 602301) acetyltransferase complex), which is a chromatin-modifying multiprotein complex (Martinez et al., 2001 [PubMed 11564863]).[supplied by OMIM, Apr 2009]

Chromosome

 2

Cytoband

 p23.3

Chromosome location (bp)

 27650812 - 27663840

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000119760 (version 83.38)

Entrez gene

 9913

UniProt

 O94864 (UniProt - Evidence at protein level)

neXtProt

 NX_O94864

Antibodypedia

 SUPT7L antibodies

PROTEIN BROWSER
SUPT7L-001
SUPT7L-002
SUPT7L-003
SUPT7L-005
SUPT7L-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SUPT7L-001
ENSP00000336750
ENST00000337768
O94864 [Direct mapping]
STAGA complex 65 subunit gamma
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003713 [transcription coactivator activity]
GO:0004402 [histone acetyltransferase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0006325 [chromatin organization]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0030914 [STAGA complex]
GO:0043966 [histone H3 acetylation]
GO:0051457 [maintenance of protein location in nucleus]
Show all
 414 aa
46.2 kDa 		No 0
SUPT7L-002
ENSP00000385436
ENST00000406540
O94864 [Direct mapping]
STAGA complex 65 subunit gamma
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003713 [transcription coactivator activity]
GO:0004402 [histone acetyltransferase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0006325 [chromatin organization]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0030914 [STAGA complex]
GO:0043966 [histone H3 acetylation]
GO:0051457 [maintenance of protein location in nucleus]
Show all
 412 aa
46 kDa 		No 0
SUPT7L-003
ENSP00000384469
ENST00000405491
O94864 [Direct mapping]
STAGA complex 65 subunit gamma
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003713 [transcription coactivator activity]
GO:0004402 [histone acetyltransferase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0006325 [chromatin organization]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0030914 [STAGA complex]
GO:0043966 [histone H3 acetylation]
GO:0051457 [maintenance of protein location in nucleus]
Show all
 412 aa
46 kDa 		No 0
SUPT7L-005
ENSP00000441110
ENST00000464789
O94864 [Direct mapping]
STAGA complex 65 subunit gamma
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003713 [transcription coactivator activity]
GO:0004402 [histone acetyltransferase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0006325 [chromatin organization]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0030914 [STAGA complex]
GO:0043966 [histone H3 acetylation]
GO:0051457 [maintenance of protein location in nucleus]
Show all
 412 aa
46 kDa 		No 0
SUPT7L-201
ENSP00000385218
ENST00000404798
O94864 [Direct mapping]
STAGA complex 65 subunit gamma
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003713 [transcription coactivator activity]
GO:0004402 [histone acetyltransferase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0006325 [chromatin organization]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0030914 [STAGA complex]
GO:0043966 [histone H3 acetylation]
GO:0051457 [maintenance of protein location in nucleus]
Show all
 279 aa
30.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.