Cell atlas - CCDC170 - The Human Protein Atlas

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CCDC170

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TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cell Junctions
	Golgi apparatus

Human cell
	Golgi Apparatus
	Plasma Membrane

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GENERAL INFORMATION
Gene name	CCDC170
Gene description	Coiled-coil domain containing 170
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the Golgi apparatus. In addition localized to the cell junctions.
RNA cell category	Group enriched (MCF7, T-47d)
Protein evidence	Evidence at protein level
Main location	Localized to the Golgi apparatus (approved)
Additional location	In addition localized to the Cell Junctions (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA027114
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Group enriched (MCF7, T-47d) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the Golgi apparatus. In addition localized to the cell junctions.

Main location

Golgi apparatus (approved)

Additional location

Cell Junctions (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA027114	MCF7	Golgi apparatus
	HPA027114	MCF7	Cell Junctions
	HPA027114	U-2 OS	Golgi apparatus
	HPA027114	U-251 MG	Golgi apparatus

GENE INFORMATION
Gene name	CCDC170 (HGNC Symbol)
Synonyms	bA282P11.1, C6orf97, FLJ23305
Description	Coiled-coil domain containing 170 (HGNC Symbol)
Entrez gene summary	The function of this gene and its encoded protein is not known. Several genome-wide association studies have implicated the region around this gene to be involved in breast cancer and bone mineral density, but no link to this specific gene has been found. [provided by RefSeq, May 2010]
Chromosome	6
Cytoband	q25.1
Chromosome location (bp)	151494030 - 151621193
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000120262 (version 83.38)
Entrez gene	80129
UniProt	Q8IYT3 (UniProt - Evidence at protein level)
neXtProt	NX_Q8IYT3
Antibodypedia	CCDC170 antibodies

PROTEIN BROWSER

CCDC170-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CCDC170-001 ENSP00000239374 ENST00000239374	Q8IYT3 [Direct mapping] Coiled-coil domain-containing protein 170 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] Show all	715 aa 82.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.