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CCDC53

GENERAL INFORMATION

Gene name

 CCDC53

Gene description

 Coiled-coil domain containing 53

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Expression in smooth muscle and epithelial tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 2 antibodies.
HPA038338 , HPA038339
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Smooth muscle

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 CCDC53 (HGNC Symbol)

Synonyms

 CGI-116

Description

 Coiled-coil domain containing 53 (HGNC Symbol)

Entrez gene summary

Chromosome

 12

Cytoband

 q23.2

Chromosome location (bp)

 102012927 - 102062149

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000120860 (version 83.38)

Entrez gene

 51019

UniProt

 Q9Y3C0 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9Y3C0

Antibodypedia

 CCDC53 antibodies

PROTEIN BROWSER
CCDC53-001
CCDC53-002
CCDC53-012

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CCDC53-001
ENSP00000240079
ENST00000240079
Q9Y3C0 [Direct mapping]
WASH complex subunit CCDC53
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0005515 [protein binding]
GO:0005769 [early endosome]
GO:0008150 [biological_process]
GO:0015031 [protein transport]
GO:0015629 [actin cytoskeleton]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0071203 [WASH complex]
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 194 aa
21.2 kDa 		No 0
CCDC53-002
ENSP00000443857
ENST00000545679
F5GZ97 [Direct mapping]
WASH complex subunit CCDC53
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0015629 [actin cytoskeleton]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0071203 [WASH complex]
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 193 aa
21 kDa 		No 0
CCDC53-012
ENSP00000443922
ENST00000542923
H0YGN0 [Direct mapping]
WASH complex subunit CCDC53
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0071203 [WASH complex]
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 107 aa
11.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.