Expression of SCPEP1 in cancer - Summary

CANCER ATLAS

Gene description

Serine carboxypeptidase 1

Protein class

Enzymes, Predicted intracellular proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA039102	HPA057200

GENE INFORMATION
Gene name	SCPEP1 (HGNC Symbol)
Synonyms	RISC
Description	Serine carboxypeptidase 1 (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	q22
Chromosome location (bp)	56978105 - 57006768
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000121064 (version 83.38)
Entrez gene	59342
UniProt	Q9HB40 (UniProt - Evidence at protein level)
neXtProt	NX_Q9HB40
Antibodypedia	SCPEP1 antibodies

PROTEIN BROWSER

SCPEP1-001	SCPEP1-005	SCPEP1-006	SCPEP1-012	SCPEP1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SCPEP1-001 ENSP00000262288 ENST00000262288	Q9HB40 [Direct mapping] Retinoid-inducible serine carboxypeptidase Show all	Enzymes Peptidases Serine-type peptidases Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004185 [serine-type carboxypeptidase activity] GO:0005829 [cytosol] GO:0006508 [proteolysis] GO:0042573 [retinoic acid metabolic process] GO:0045776 [negative regulation of blood pressure] GO:0045909 [positive regulation of vasodilation] GO:0070062 [extracellular exosome] Show all	452 aa 50.8 kDa	Yes	0
SCPEP1-005 ENSP00000461694 ENST00000575395	I3L506 [Direct mapping] Retinoid-inducible serine carboxypeptidase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004185 [serine-type carboxypeptidase activity] GO:0006508 [proteolysis] Show all	95 aa 10.4 kDa	No	0
SCPEP1-006 ENSP00000461663 ENST00000572710	I3L4Z3 [Direct mapping] Retinoid-inducible serine carboxypeptidase Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004185 [serine-type carboxypeptidase activity] GO:0006508 [proteolysis] Show all	176 aa 19.7 kDa	Yes	0
SCPEP1-012 ENSP00000461678 ENST00000573239	I3L4Z9 [Direct mapping] Retinoid-inducible serine carboxypeptidase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004185 [serine-type carboxypeptidase activity] GO:0006508 [proteolysis] Show all	135 aa 15.4 kDa	No	0
SCPEP1-201 ENSP00000487541 ENST00000631024	I3L2N6 [Direct mapping] Retinoid-inducible serine carboxypeptidase Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004185 [serine-type carboxypeptidase activity] GO:0006508 [proteolysis] Show all	147 aa 16.5 kDa	Yes	0