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Many thyroid, skin, cervical, endometrial and testis cancers along with a few colorectal, lung, urothelial and renal cancers displayed moderate to strong cytoplasmic and occasional membranous staining. Remaining malignant cells were weakly stained or negative.
GENE INFORMATION
Gene name
NXPH1
Synonyms
Description
Neurexophilin 1 (HGNC Symbol)
Entrez gene summary
This gene is a member of the neurexophilin family and encodes a secreted protein with a variable N-terminal domain, a highly conserved, N-glycosylated central domain, a short linker region, and a cysteine-rich C-terminal domain. This protein forms a very tight complex with alpha neurexins, a group of proteins that promote adhesion between dendrites and axons. [provided by RefSeq, Jul 2008]
