Tissue expression of ATXN3L - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

ATXN3L

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	ATXN3L
Gene description	Ataxin 3-like
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (testis)
GTEx:	Tissue enriched (testis)
FANTOM5:	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification. Caution, targets protein from more than one gene.
Reliability score	Uncertain based on 2 antibodies. HPA024123 , HPA027539
	SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)

GENE INFORMATION
Gene name	ATXN3L (HGNC Symbol)
Synonyms	MJDL
Description	Ataxin 3-like (HGNC Symbol)
Entrez gene summary	This intronless gene may be a pseudogene (PMID:11450850). This gene is similar to the multi-exon gene which encodes ataxin 3 and contains a coding region which could encode a protein similar to ataxin 3. Mutations in the gene encoding ataxin 3 are associated with Machado-Joseph disease. [provided by RefSeq, Sep 2011]
Chromosome	X
Cytoband	p22.2
Chromosome location (bp)	13318236 - 13319952
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000123594 (version 83.38)
Entrez gene	92552
UniProt	Q9H3M9 (UniProt - Uncertain)
neXtProt	NX_Q9H3M9
Antibodypedia	ATXN3L antibodies

PROTEIN BROWSER

ATXN3L-001	ATXN3L-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ATXN3L-001 ENSP00000369996 ENST00000380622	Q9H3M9 [Direct mapping] Putative ataxin-3-like protein Show all	Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Show all	GO:0001012 [RNA polymerase II regulatory region DNA binding] GO:0004407 [histone deacetylase activity] GO:0004843 [ubiquitin-specific protease activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005759 [mitochondrial matrix] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0006511 [ubiquitin-dependent protein catabolic process] GO:0006515 [misfolded or incompletely synthesized protein catabolic process] GO:0008242 [omega peptidase activity] GO:0016579 [protein deubiquitination] GO:0031966 [mitochondrial membrane] GO:0034605 [cellular response to heat] GO:0035520 [monoubiquitinated protein deubiquitination] GO:0035640 [exploration behavior] GO:0042405 [nuclear inclusion body] GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process] GO:0070932 [histone H3 deacetylation] GO:0071218 [cellular response to misfolded protein] Show all	355 aa 40.7 kDa	No	0
ATXN3L-201 ENSP00000479386 ENST00000622204	A0A087WVE5 [Direct mapping] Putative ataxin-3-like protein Show all	Predicted intracellular proteins Show all	GO:0006508 [proteolysis] GO:0008242 [omega peptidase activity] Show all	162 aa 18.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.