Fields »
ABOUT
HELP
BLOG
NMI

GENERAL INFORMATION

Gene name

 NMI

Gene description

 N-myc (and STAT) interactor

Protein class

 Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in most tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data.

Reliability score

 Approved based on 1 antibody.
HPA008588
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 NMI

Synonyms

Description

 N-myc (and STAT) interactor (HGNC Symbol)

Entrez gene summary

 NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias. [provided by RefSeq, Jul 2008]

Chromosome

 2

Cytoband

 q23.3

Chromosome location (bp)

 151270465 - 151290057

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000123609 (version 83.38)

Entrez gene

 9111

UniProt

 Q13287 (UniProt - Evidence at protein level)

neXtProt

 NX_Q13287

Antibodypedia

 NMI antibodies

PROTEIN BROWSER
NMI-001
NMI-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
NMI-001
ENSP00000243346
ENST00000243346
Q13287 [Direct mapping]
N-myc-interactor
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003712 [transcription cofactor activity]
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0006954 [inflammatory response]
GO:0007259 [JAK-STAT cascade]
GO:0032480 [negative regulation of type I interferon production]
GO:0045355 [negative regulation of interferon-alpha biosynthetic process]
GO:0045358 [negative regulation of interferon-beta biosynthetic process]
GO:0045824 [negative regulation of innate immune response]
GO:1902524 [positive regulation of protein K48-linked ubiquitination]
GO:1903506 [regulation of nucleic acid-templated transcription]
Show all
 307 aa
35.1 kDa 		No 0
NMI-003
ENSP00000387373
ENST00000414946
C9JW17 [Direct mapping]
N-myc-interactor
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 29 aa
3.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.