We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
Fields »
 

Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
ABOUT
HELP
BLOG
  • THE HUMAN PROTEOME
  • THE HUMAN TISSUES
  • THE HUMAN CELL
  • PROTEIN CLASSES
  • PROTEIN EVIDENCE
    • NEWS
    • BLOG
    • EVENTS
    • PRESS ROOM
    • LEARN
    • DICTIONARY
    • METHODS
    • CELL LINES
  • THE PROJECT
  • INTRODUCTION
  • ORGANIZATION
  • PUBLICATIONS
  • PUBLICATION DATA
  • ANTIBODY SUBMISSION
  • ANTIBODY AVAILABILITY
  • LINKS
  • CONTACT
  • TECHNICAL DATA
  • ANTIBODY VALIDATION
  • ASSAYS & ANNOTATION
  • DISCLAIMER
  • DOWNLOADABLE DATA
  • HELP & FAQ
  • LICENCE & CITATION
  • PRIVACY STATEMENT
  • RELEASE HISTORY
RBPJL
  • premium

    TISSUE

  • CELL

  • CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

RBPJL

Gene description

Recombination signal binding protein for immunoglobulin kappa J region-like

Protein class

Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

4
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Tissue enriched (pancreas)
GTEx:Tissue enriched (pancreas)
FANTOM5:Tissue enriched (pancreas)

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in subset of cells in islets of Langerhans.

DATA RELIABILITY

Data reliability
description

Antibody staining consistent with RNA expression data.

Reliability score

Supported based on 1 antibody.
CAB006846
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Pancreas

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (pancreas)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (pancreas)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (pancreas)

GENE INFORMATION

Gene name

RBPJL (HGNC Symbol)

Synonyms

RBP-L, RBPSUHL, SUH, SUHL

Description

Recombination signal binding protein for immunoglobulin kappa J region-like (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the suppressor of hairless protein family. A similar protein in mouse is a transcription factor that binds to DNA sequences almost identical to that bound by the Notch receptor signaling pathway transcription factor recombining binding protein J. The mouse protein has been shown to activate transcription in concert with Epstein-Barr virus nuclear antigen-2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Chromosome

20

Cytoband

q13.12

Chromosome location (bp)

45306851 - 45317824

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000124232 (version 83.38)

Entrez gene

11317

UniProt

Q9UBG7 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9UBG7

Antibodypedia

RBPJL antibodies

PROTEIN BROWSER

RBPJL-001
RBPJL-002
RBPJL-003
RBPJL-004

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RBPJL-001
ENSP00000361828
ENST00000372743
Q9UBG7 [Direct mapping]
Recombining binding protein suppressor of hairless-like protein
Show all
Predicted intracellular proteins
Transcription factors
   Immunoglobulin fold
Show all
GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding]
GO:0000982 [transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0007165 [signal transduction]
Show all
516 aa
56.6 kDa
No 0
RBPJL-002
ENSP00000341243
ENST00000343694
Q9UBG7 [Direct mapping]
Recombining binding protein suppressor of hairless-like protein
Show all
Predicted intracellular proteins
Transcription factors
   Immunoglobulin fold
Show all
GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding]
GO:0000982 [transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0003677 [DNA binding]
GO:0003682 [chromatin binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005634 [nucleus]
GO:0005667 [transcription factor complex]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0007165 [signal transduction]
GO:0045893 [positive regulation of transcription, DNA-templated]
Show all
517 aa
56.8 kDa
No 0
RBPJL-003
ENSP00000361826
ENST00000372741
Q5QPV1 [Direct mapping]
Recombining binding protein suppressor of hairless (Drosophila)-like, isoform CRA_a; Recombining-binding protein suppressor of hairless-like protein
Show all
Predicted intracellular proteins
Show all
GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding]
GO:0000982 [transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005634 [nucleus]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
Show all
471 aa
51.3 kDa
No 0
RBPJL-004
ENSP00000483978
ENST00000464504
A0A087X185 [Direct mapping]
Recombining-binding protein suppressor of hairless-like protein
Show all
Predicted intracellular proteins
Show all
GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding]
GO:0000982 [transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0005634 [nucleus]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
Show all
184 aa
19.5 kDa
No 0

Contact

  • BLOG
  • PRESS ROOM
  • contact@proteinatlas.org

The Project

  • INTRODUCTION
  • ORGANIZATION
  • PUBLICATIONS
  • DOWNLOADABLE DATA

The Human Protein Atlas

  • ANTIBODY AVAILABILITY
  • LICENCE & CITATION
  • HELP & FAQ
The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.