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Many urothelial cancers and thyroid cancers along with a few lymphomas, breast, skin and testis cancers displayed moderate cytoplasmic positivity. Remaining cancer cells were weakly stained or negative.
Most cancer cells showed weak to moderate nuclear membranous staining and/or cytoplasmic positivity. Several cases of hepatocellular carcinomas, basal cell carcinomas, gastric, renal and lung cancers were negative.
GENE INFORMATION
Gene name
NAGK (HGNC Symbol)
Synonyms
GNK
Description
N-acetylglucosamine kinase (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the N-acetylhexosamine kinase family. The encoded protein catalyzes the conversion of N-acetyl-D-glucosamine to N-acetyl-D-glucosamine 6-phosphate, and is the major mammalian enzyme which recovers amino sugars. [provided by RefSeq, Nov 2011]