Cell atlas - NAGK - The Human Protein Atlas

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NAGK

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TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Nucleus

Human cell
	Cytosol
	Nucleoplasm

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GENERAL INFORMATION
Gene name	NAGK
Gene description	N-acetylglucosamine kinase
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	10
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleus & cytosol.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleus (approved), Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA035207
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleus & cytosol.

Main location

Nucleus (approved), Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA035207	A-431	Nucleus
	HPA035207	A-431	Cytosol
	HPA035207	U-2 OS	Cytosol
	HPA035207	U-251 MG	No staining

GENE INFORMATION
Gene name	NAGK (HGNC Symbol)
Synonyms	GNK
Description	N-acetylglucosamine kinase (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the N-acetylhexosamine kinase family. The encoded protein catalyzes the conversion of N-acetyl-D-glucosamine to N-acetyl-D-glucosamine 6-phosphate, and is the major mammalian enzyme which recovers amino sugars. [provided by RefSeq, Nov 2011]
Chromosome	2
Cytoband	p13.3
Chromosome location (bp)	71064344 - 71079805
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000124357 (version 83.38)
Entrez gene	55577
UniProt	Q9UJ70 (UniProt - Evidence at protein level)
neXtProt	NX_Q9UJ70
Antibodypedia	NAGK antibodies

PROTEIN BROWSER

NAGK-001	NAGK-002	NAGK-003	NAGK-025	NAGK-026	NAGK-027	NAGK-029	NAGK-030	NAGK-032	NAGK-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NAGK-001 ENSP00000411846 ENST00000443938	H7C3G9 [Direct mapping] N-acetyl-D-glucosamine kinase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		340 aa 36.9 kDa	No	0
NAGK-002 ENSP00000396070 ENST00000418807	C9JEV6 [Direct mapping] N-acetyl-D-glucosamine kinase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		293 aa 32 kDa	No	0
NAGK-003 ENSP00000389087 ENST00000455662	Q9UJ70 [Direct mapping] N-acetyl-D-glucosamine kinase Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0006051 [N-acetylmannosamine metabolic process] GO:0019262 [N-acetylneuraminate catabolic process] GO:0045127 [N-acetylglucosamine kinase activity] GO:0046835 [carbohydrate phosphorylation] GO:0070062 [extracellular exosome] Show all	390 aa 42 kDa	No	0
NAGK-025 ENSP00000436326 ENST00000531934	E9PPU6 [Direct mapping] N-acetyl-D-glucosamine kinase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		94 aa 10.8 kDa	No	0
NAGK-026 ENSP00000404531 ENST00000443872	H7C286 [Direct mapping] N-acetyl-D-glucosamine kinase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		196 aa 22 kDa	No	0
NAGK-027 ENSP00000435207 ENST00000533981	H0YE82 [Direct mapping] N-acetyl-D-glucosamine kinase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		84 aa 8.8 kDa	No	0
NAGK-029 ENSP00000431204 ENST00000529236	H0YC94 [Direct mapping] N-acetyl-D-glucosamine kinase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		136 aa 14.6 kDa	No	0
NAGK-030 ENSP00000437192 ENST00000524537	H0YF44 [Direct mapping] N-acetyl-D-glucosamine kinase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		109 aa 12 kDa	No	0
NAGK-032 ENSP00000244204 ENST00000244204	Q9UJ70 [Direct mapping] N-acetyl-D-glucosamine kinase Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0006051 [N-acetylmannosamine metabolic process] GO:0019262 [N-acetylneuraminate catabolic process] GO:0045127 [N-acetylglucosamine kinase activity] GO:0046835 [carbohydrate phosphorylation] GO:0070062 [extracellular exosome] Show all	344 aa 37.4 kDa	No	0
NAGK-201 ENSP00000477639 ENST00000613852	Q9UJ70 [Direct mapping] N-acetyl-D-glucosamine kinase Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0006044 [N-acetylglucosamine metabolic process] GO:0006051 [N-acetylmannosamine metabolic process] GO:0009384 [N-acylmannosamine kinase activity] GO:0019262 [N-acetylneuraminate catabolic process] GO:0045127 [N-acetylglucosamine kinase activity] GO:0046835 [carbohydrate phosphorylation] GO:0070062 [extracellular exosome] Show all	390 aa 42 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.