Expression of IRGC in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Immunity-related GTPase family, cinema

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA046769	HPA060064

GENE INFORMATION
Gene name	IRGC (HGNC Symbol)
Synonyms	CINEMA, Iigp5, IRGC1
Description	Immunity-related GTPase family, cinema (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	q13.31
Chromosome location (bp)	43716010 - 43720021
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000124449 (version 83.38)
Entrez gene	56269
UniProt	Q6NXR0 (UniProt - Evidence at transcript level)
neXtProt	NX_Q6NXR0
Antibodypedia	IRGC antibodies

PROTEIN BROWSER

IRGC-001	IRGC-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
IRGC-001 ENSP00000244314 ENST00000244314	Q6NXR0 [Direct mapping] Interferon-inducible GTPase 5 J7NNX4 [Target identity:100%; Query identity:100%] Immunity-related GTPase family, cinema, isoform CRA_b; Interferon-gamma-inducible GTPase IFGGE protein Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005525 [GTP binding] GO:0008152 [metabolic process] GO:0016020 [membrane] GO:0016787 [hydrolase activity] Show all	463 aa 50.3 kDa	No	0
IRGC-002 ENSP00000471425 ENST00000596627	M0R0T1 [Direct mapping] Interferon-inducible GTPase 5 Show all	Predicted intracellular proteins Show all	GO:0005525 [GTP binding] GO:0016020 [membrane] Show all	275 aa 30.2 kDa	No	0