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MRPS26

CANCER ATLAS

Gene description

 Mitochondrial ribosomal protein S26

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA045472

GENE INFORMATION

Gene name

 MRPS26 (HGNC Symbol)

Synonyms

 C20orf193, dJ534B8.3, MRP-S13, MRP-S26, RPMS13

Description

 Mitochondrial ribosomal protein S26 (HGNC Symbol)

Entrez gene summary

 Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. This gene lies adjacent to and downstream of the gonadotropin-releasing hormone precursor gene. [provided by RefSeq, Jul 2008]

Chromosome

 20

Cytoband

 p13

Chromosome location (bp)

 3045945 - 3048254

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000125901 (version 83.38)

Entrez gene

 64949

UniProt

 Q9BYN8 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9BYN8

Antibodypedia

 MRPS26 antibodies

PROTEIN BROWSER
MRPS26-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MRPS26-001
ENSP00000369682
ENST00000380325
Q9BYN8 [Direct mapping]
28S ribosomal protein S26, mitochondrial
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005654 [nucleoplasm]
GO:0005739 [mitochondrion]
GO:0005743 [mitochondrial inner membrane]
GO:0005763 [mitochondrial small ribosomal subunit]
GO:0006996 [organelle organization]
GO:0032543 [mitochondrial translation]
GO:0042769 [DNA damage response, detection of DNA damage]
GO:0043043 [peptide biosynthetic process]
GO:0044822 [poly(A) RNA binding]
GO:0070124 [mitochondrial translational initiation]
GO:0070125 [mitochondrial translational elongation]
GO:0070126 [mitochondrial translational termination]
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 205 aa
24.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.