Fields »
ABOUT
HELP
BLOG
MRPS26

Please wait until image is loaded before changing channels

GENERAL INFORMATION

Gene name

 MRPS26

Gene description

 Mitochondrial ribosomal protein S26

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

 Mainly localized to the mitochondria.

RNA cell category

 Expressed in all

Protein evidence

 Evidence at protein level

Main location

 Localized to the Mitochondria (validated)

DATA RELIABILITY

Reliability score

 Validated based on 2 antibodies.
HPA045472 , HPA054610
SHOW MORE

ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Mainly localized to the mitochondria.

Main location

 Mitochondria (validated)

 

 

 
Toggle channels
Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA045472 A-431 Mitochondria
HPA045472 U-2 OS Mitochondria
HPA045472 U-251 MG Mitochondria
HPA054610 A-431 No staining    
HPA054610 U-2 OS Mitochondria
HPA054610 U-251 MG Nucleoplasm
Mitochondria

GENE INFORMATION

Gene name

 MRPS26 (HGNC Symbol)

Synonyms

 C20orf193, dJ534B8.3, MRP-S13, MRP-S26, RPMS13

Description

 Mitochondrial ribosomal protein S26 (HGNC Symbol)

Entrez gene summary

 Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. This gene lies adjacent to and downstream of the gonadotropin-releasing hormone precursor gene. [provided by RefSeq, Jul 2008]

Chromosome

 20

Cytoband

 p13

Chromosome location (bp)

 3045945 - 3048254

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000125901 (version 83.38)

Entrez gene

 64949

UniProt

 Q9BYN8 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9BYN8

Antibodypedia

 MRPS26 antibodies

PROTEIN BROWSER
MRPS26-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MRPS26-001
ENSP00000369682
ENST00000380325
Q9BYN8 [Direct mapping]
28S ribosomal protein S26, mitochondrial
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005654 [nucleoplasm]
GO:0005739 [mitochondrion]
GO:0005743 [mitochondrial inner membrane]
GO:0005763 [mitochondrial small ribosomal subunit]
GO:0006996 [organelle organization]
GO:0032543 [mitochondrial translation]
GO:0042769 [DNA damage response, detection of DNA damage]
GO:0043043 [peptide biosynthetic process]
GO:0044822 [poly(A) RNA binding]
GO:0070124 [mitochondrial translational initiation]
GO:0070125 [mitochondrial translational elongation]
GO:0070126 [mitochondrial translational termination]
Show all
 205 aa
24.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.