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FFAR2

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GENERAL INFORMATION

Gene name

 FFAR2

Gene description

 Free fatty acid receptor 2

Protein class

 G-protein coupled receptors
Predicted membrane proteins

Predicted localization

 Membrane

Number of transcripts

 2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Cell line enhanced (HMC-1, U-937)

Protein evidence

 Evidence at protein level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (HMC-1, U-937)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 FFAR2 (HGNC Symbol)

Synonyms

 FFA2R, GPR43

Description

 Free fatty acid receptor 2 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the GP40 family of G protein-coupled receptors that are clustered together on chromosome 19. The encoded protein is a receptor for short chain free fatty acids and may be involved in the inflammatory response and in regulating lipid plasma levels. [provided by RefSeq, Apr 2009]

Chromosome

 19

Cytoband

 q13.12

Chromosome location (bp)

 35443907 - 35451767

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000126262 (version 83.38)

Entrez gene

 2867

UniProt

 O15552 (UniProt - Evidence at protein level)

neXtProt

 NX_O15552

Antibodypedia

 FFAR2 antibodies

PROTEIN BROWSER
FFAR2-001
FFAR2-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
FFAR2-001
ENSP00000473159
ENST00000599180
O15552 [Direct mapping]
Free fatty acid receptor 2
C6KYL4 [Target identity:100%; Query identity:100%]
Free fatty acid receptor 2
Show all
G-protein coupled receptors
   GPCRs excl olfactory receptors
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   GPCRHMM predicted membrane proteins
   # TM segments-based
   7TM proteins predicted by MDM
Show all
GO:0002232 [leukocyte chemotaxis involved in inflammatory response]
GO:0002385 [mucosal immune response]
GO:0002673 [regulation of acute inflammatory response]
GO:0002720 [positive regulation of cytokine production involved in immune response]
GO:0002752 [cell surface pattern recognition receptor signaling pathway]
GO:0002879 [positive regulation of acute inflammatory response to non-antigenic stimulus]
GO:0004930 [G-protein coupled receptor activity]
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0007186 [G-protein coupled receptor signaling pathway]
GO:0008289 [lipid binding]
GO:0016021 [integral component of membrane]
GO:0019915 [lipid storage]
GO:0032722 [positive regulation of chemokine production]
GO:0042593 [glucose homeostasis]
GO:0042995 [cell projection]
GO:0045444 [fat cell differentiation]
GO:0071398 [cellular response to fatty acid]
GO:0090276 [regulation of peptide hormone secretion]
GO:2000484 [positive regulation of interleukin-8 secretion]
Show all
 330 aa
37.1 kDa 		No 7
FFAR2-201
ENSP00000246549
ENST00000246549
O15552 [Direct mapping]
Free fatty acid receptor 2
C6KYL4 [Target identity:100%; Query identity:100%]
Free fatty acid receptor 2
Show all
G-protein coupled receptors
   GPCRs excl olfactory receptors
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   GPCRHMM predicted membrane proteins
   # TM segments-based
   7TM proteins predicted by MDM
Show all
GO:0002232 [leukocyte chemotaxis involved in inflammatory response]
GO:0002385 [mucosal immune response]
GO:0002673 [regulation of acute inflammatory response]
GO:0002720 [positive regulation of cytokine production involved in immune response]
GO:0002752 [cell surface pattern recognition receptor signaling pathway]
GO:0002879 [positive regulation of acute inflammatory response to non-antigenic stimulus]
GO:0004930 [G-protein coupled receptor activity]
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0007186 [G-protein coupled receptor signaling pathway]
GO:0008289 [lipid binding]
GO:0016021 [integral component of membrane]
GO:0019915 [lipid storage]
GO:0032722 [positive regulation of chemokine production]
GO:0042593 [glucose homeostasis]
GO:0045444 [fat cell differentiation]
GO:0071398 [cellular response to fatty acid]
GO:0090276 [regulation of peptide hormone secretion]
GO:2000484 [positive regulation of interleukin-8 secretion]
Show all
 330 aa
37.1 kDa 		No 7

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.