Cell atlas - RGS13 - The Human Protein Atlas

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RGS13

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	RGS13
Gene description	Regulator of G-protein signaling 13
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enriched (Daudi)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enriched (Daudi) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	RGS13
Synonyms
Description	Regulator of G-protein signaling 13 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown. Two transcript variants encoding the same isoform exist. [provided by RefSeq, Jul 2008]
Chromosome	1
Cytoband	q31.2
Chromosome location (bp)	192636138 - 192660306
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000127074 (version 83.38)
Entrez gene	6003
UniProt	O14921 (UniProt - Evidence at transcript level)
neXtProt	NX_O14921
Antibodypedia	RGS13 antibodies

PROTEIN BROWSER

RGS13-001	RGS13-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RGS13-001 ENSP00000375853 ENST00000391995	O14921 [Direct mapping] Regulator of G-protein signaling 13 A0A024R989 [Target identity:100%; Query identity:100%] Regulator of G-protein signalling 13, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005096 [GTPase activator activity] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] GO:0043547 [positive regulation of GTPase activity] Show all	159 aa 19.1 kDa	No	0
RGS13-201 ENSP00000442837 ENST00000543215	O14921 [Direct mapping] Regulator of G-protein signaling 13 A0A024R989 [Target identity:100%; Query identity:100%] Regulator of G-protein signalling 13, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005096 [GTPase activator activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0043547 [positive regulation of GTPase activity] GO:0045744 [negative regulation of G-protein coupled receptor protein signaling pathway] Show all	159 aa 19.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.