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Most cases of colorectal, pancreas and breast cancers as well as several cases of malignant melanomas, lung, prostate, skin, liver and gastric cancers showed moderate to strong cytoplasmic and membranous staining. Nuclear or nucleolar positivity was observed in a few cases. Remaining malignant tissues were in general weakly stained or negative.
GENE INFORMATION
Gene name
ABHD8 (HGNC Symbol)
Synonyms
FLJ11743, MGC14280, MGC2512
Description
Abhydrolase domain containing 8 (HGNC Symbol)
Entrez gene summary
This gene is upstream of, and in a head-to-head orientation with the gene for the mitochondrial ribosomal protein L34. The predicted protein contains alpha/beta hydrolase fold and secretory lipase domains. [provided by RefSeq, Jul 2008]