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Most malignancies showed moderate cytoplasmic staining. Several embryonal carcinomas in testis were strongly stained. A majority of malignant lymphomas and several lung and gastric cancers were weakly stained or negative.
GENE INFORMATION
Gene name
AAMP
Synonyms
Description
Angio-associated, migratory cell protein (HGNC Symbol)
Entrez gene summary
The gene is a member of the immunoglobulin superfamily. The encoded protein is associated with angiogenesis, with potential roles in endothelial tube formation and the migration of endothelial cells. It may also regulate smooth muscle cell migration via the RhoA pathway. The encoded protein can bind to heparin and may mediate heparin-sensitive cell adhesion. [provided by RefSeq, Oct 2014]