Expression of THAP10 in cancer - Summary

CANCER ATLAS

Gene description

THAP domain containing 10

Protein class

Predicted intracellular proteins, Transcription factors

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA041416

GENE INFORMATION
Gene name	THAP10
Synonyms
Description	THAP domain containing 10 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of a family of proteins sharing an N-terminal Thanatos-associated domain. The Thanatos-associated domain contains a zinc finger signature similar to DNA-binding domains. This gene is part of a bidirectional gene pair on the long arm of chromosome 15 that is regulated by estrogen and may play a role in breast cancer. [provided by RefSeq, Nov 2010]
Chromosome	15
Cytoband	q23
Chromosome location (bp)	70881342 - 70892785
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000129028 (version 83.38)
Entrez gene	56906
UniProt	Q9P2Z0 (UniProt - Evidence at protein level)
neXtProt	NX_Q9P2Z0
Antibodypedia	THAP10 antibodies

PROTEIN BROWSER

THAP10-001	THAP10-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
THAP10-001 ENSP00000249861 ENST00000249861	Q9P2Z0 [Direct mapping] THAP domain-containing protein 10 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0046872 [metal ion binding] Show all	257 aa 28.4 kDa	No	0
THAP10-002 ENSP00000453920 ENST00000560604	H0YN95 [Direct mapping] THAP domain-containing protein 10 Show all	Predicted intracellular proteins Show all		127 aa 14.1 kDa	No	0