Cell atlas - THAP10 - The Human Protein Atlas

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THAP10

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Nucleoplasm

Human cell
	Cytosol
	Nucleoplasm

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GENERAL INFORMATION
Gene name	THAP10
Gene description	THAP domain containing 10
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the cytosol & nucleoplasm.
RNA cell category	Cell line enhanced (U-2197)
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (approved), Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA041416
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (U-2197) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the cytosol & nucleoplasm.

Main location

Nucleoplasm (approved), Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA041416	A-431	Nucleoplasm
	HPA041416	A-431	Cytosol
	HPA041416	U-2 OS	Nucleoplasm
	HPA041416	U-2 OS	Cytosol

GENE INFORMATION
Gene name	THAP10
Synonyms
Description	THAP domain containing 10 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of a family of proteins sharing an N-terminal Thanatos-associated domain. The Thanatos-associated domain contains a zinc finger signature similar to DNA-binding domains. This gene is part of a bidirectional gene pair on the long arm of chromosome 15 that is regulated by estrogen and may play a role in breast cancer. [provided by RefSeq, Nov 2010]
Chromosome	15
Cytoband	q23
Chromosome location (bp)	70881342 - 70892785
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000129028 (version 83.38)
Entrez gene	56906
UniProt	Q9P2Z0 (UniProt - Evidence at protein level)
neXtProt	NX_Q9P2Z0
Antibodypedia	THAP10 antibodies

PROTEIN BROWSER

THAP10-001	THAP10-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
THAP10-001 ENSP00000249861 ENST00000249861	Q9P2Z0 [Direct mapping] THAP domain-containing protein 10 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0046872 [metal ion binding] Show all	257 aa 28.4 kDa	No	0
THAP10-002 ENSP00000453920 ENST00000560604	H0YN95 [Direct mapping] THAP domain-containing protein 10 Show all	Predicted intracellular proteins Show all		127 aa 14.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.