Tissue expression of PALLD - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	PALLD
Gene description	Palladin, cytoskeletal associated protein
Protein class	Disease related genes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	12
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Mixed
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Mixed
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	PALLD (HGNC Symbol)
Synonyms	CGI-151, KIAA0992, SIH002
Description	Palladin, cytoskeletal associated protein (HGNC Symbol)
Entrez gene summary	This gene encodes a cytoskeletal protein that is required for organizing the actin cytoskeleton. The protein is a component of actin-containing microfilaments, and it is involved in the control of cell shape, adhesion, and contraction. Polymorphisms in this gene are associated with a susceptibility to pancreatic cancer type 1, and also with a risk for myocardial infarction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Chromosome	4
Cytoband	q32.3
Chromosome location (bp)	168497066 - 168928457
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000129116 (version 83.38)
Entrez gene	23022
UniProt	Q8WX93 (UniProt - Evidence at protein level)
neXtProt	NX_Q8WX93
Antibodypedia	PALLD antibodies

PROTEIN BROWSER

PALLD-001	PALLD-002	PALLD-003	PALLD-004	PALLD-005	PALLD-007	PALLD-008	PALLD-009	PALLD-010	PALLD-011	PALLD-012	PALLD-013

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PALLD-001 ENSP00000261509 ENST00000261509	Q8WX93 [Direct mapping] Palladin B2RTX2 [Target identity:100%; Query identity:100%] Palladin, cytoskeletal associated protein Show all	Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001726 [ruffle] GO:0003779 [actin binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0005884 [actin filament] GO:0005886 [plasma membrane] GO:0005925 [focal adhesion] GO:0007010 [cytoskeleton organization] GO:0015629 [actin cytoskeleton] GO:0030018 [Z disc] GO:0030027 [lamellipodium] GO:0051371 [muscle alpha-actinin binding] Show all	1106 aa 122 kDa	No	0
PALLD-002 ENSP00000425556 ENST00000505667	Q8WX93 [Direct mapping] Palladin Show all	Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001726 [ruffle] GO:0003334 [keratinocyte development] GO:0003382 [epithelial cell morphogenesis] GO:0003779 [actin binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0005884 [actin filament] GO:0005886 [plasma membrane] GO:0005925 [focal adhesion] GO:0007010 [cytoskeleton organization] GO:0015629 [actin cytoskeleton] GO:0030018 [Z disc] GO:0030027 [lamellipodium] GO:0030036 [actin cytoskeleton organization] GO:0051371 [muscle alpha-actinin binding] Show all	1123 aa 123.7 kDa	No	0
PALLD-003 ENSP00000423063 ENST00000508898	H0Y952 [Direct mapping] Palladin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	512 aa 56.5 kDa	No	0
PALLD-004 ENSP00000426947 ENST00000512127	Q8WX93 [Direct mapping] Palladin Show all	Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001726 [ruffle] GO:0003779 [actin binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0005884 [actin filament] GO:0005886 [plasma membrane] GO:0005925 [focal adhesion] GO:0007010 [cytoskeleton organization] GO:0015629 [actin cytoskeleton] GO:0030018 [Z disc] GO:0030027 [lamellipodium] GO:0051371 [muscle alpha-actinin binding] Show all	777 aa 85.9 kDa	No	0
PALLD-005 ENSP00000424016 ENST00000507735	Q8WX93 [Direct mapping] Palladin Show all	Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001726 [ruffle] GO:0003779 [actin binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0005884 [actin filament] GO:0005886 [plasma membrane] GO:0005925 [focal adhesion] GO:0007010 [cytoskeleton organization] GO:0015629 [actin cytoskeleton] GO:0030018 [Z disc] GO:0030027 [lamellipodium] GO:0051371 [muscle alpha-actinin binding] Show all	672 aa 73.3 kDa	No	0
PALLD-007 ENSP00000423640 ENST00000511948	D6R948 [Direct mapping] Palladin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		28 aa 3.2 kDa	No	0
PALLD-008 ENSP00000424121 ENST00000504519	D6RBH5 [Direct mapping] Palladin Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	83 aa 8.9 kDa	No	0
PALLD-009 ENSP00000422016 ENST00000513245	D6R9Z5 [Direct mapping] Palladin Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		71 aa 7.5 kDa	No	0
PALLD-010 ENSP00000424288 ENST00000503457	D6RBB1 [Direct mapping] Palladin Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	96 aa 10.3 kDa	No	0
PALLD-011 ENSP00000422135 ENST00000510998	D6R9F5 [Direct mapping] Palladin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		90 aa 10.4 kDa	No	0
PALLD-012 ENSP00000377327 ENST00000393726	F8WA26 [Direct mapping] Palladin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	164 aa 18.5 kDa	No	0
PALLD-013 ENSP00000425729 ENST00000503290	H0YA05 [Direct mapping] Palladin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	160 aa 17.5 kDa	No	0