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NGDN

CANCER ATLAS

Gene description

 Neuroguidin, EIF4E binding protein

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA000944

GENE INFORMATION

Gene name

 NGDN (HGNC Symbol)

Synonyms

 C14orf120, DKFZP564O092, LCP5, lpd-2, NGD

Description

 Neuroguidin, EIF4E binding protein (HGNC Symbol)

Entrez gene summary

 Neuroguidin is an EIF4E (MIM 133440)-binding protein that interacts with CPEB (MIM 607342) and functions as a translational regulatory protein during development of the vertebrate nervous system (Jung et al., 2006 [PubMed 16705177]).[supplied by OMIM, Mar 2008]

Chromosome

 14

Cytoband

 q11.2

Chromosome location (bp)

 23469688 - 23509862

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000129460 (version 83.38)

Entrez gene

 25983

UniProt

 Q8NEJ9 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8NEJ9

Antibodypedia

 NGDN antibodies

PROTEIN BROWSER
NGDN-001
NGDN-002
NGDN-006
NGDN-010
NGDN-012

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
NGDN-001
ENSP00000386134
ENST00000408901
Q8NEJ9 [Direct mapping]
Neuroguidin
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000462 [maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)]
GO:0000775 [chromosome, centromeric region]
GO:0005515 [protein binding]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0006417 [regulation of translation]
GO:0030175 [filopodium]
GO:0030424 [axon]
GO:0030425 [dendrite]
GO:0032040 [small-subunit processome]
GO:0044822 [poly(A) RNA binding]
Show all
 315 aa
35.9 kDa 		No 0
NGDN-002
ENSP00000380340
ENST00000397154
Q8NEJ9 [Direct mapping]
Neuroguidin
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000462 [maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)]
GO:0000775 [chromosome, centromeric region]
GO:0005515 [protein binding]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0006417 [regulation of translation]
GO:0030175 [filopodium]
GO:0030424 [axon]
GO:0030425 [dendrite]
GO:0032040 [small-subunit processome]
GO:0044822 [poly(A) RNA binding]
Show all
 311 aa
35.2 kDa 		No 0
NGDN-006
ENSP00000451942
ENST00000556699
H0YJQ1 [Direct mapping]
Neuroguidin
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000462 [maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)]
GO:0005730 [nucleolus]
GO:0032040 [small-subunit processome]
Show all
 74 aa
8.5 kDa 		No 0
NGDN-010
ENSP00000451779
ENST00000555128
G3V4G1 [Direct mapping]
Neuroguidin
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000462 [maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)]
GO:0005730 [nucleolus]
GO:0032040 [small-subunit processome]
Show all
 142 aa
15.7 kDa 		No 0
NGDN-012
ENSP00000450659
ENST00000556483
H0YJ17 [Direct mapping]
Neuroguidin
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000462 [maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)]
GO:0005730 [nucleolus]
GO:0032040 [small-subunit processome]
Show all
 263 aa
29.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.