Expression of RAB2B in cancer - Summary

CANCER ATLAS

Gene description

RAB2B, member RAS oncogene family

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Urothelial cancer

STAINING SUMMARY

HPA050292

GENE INFORMATION
Gene name	RAB2B (HGNC Symbol)
Synonyms	FLJ14824
Description	RAB2B, member RAS oncogene family (HGNC Symbol)
Entrez gene summary	Members of the Rab protein family are nontransforming monomeric GTP-binding proteins of the Ras superfamily that contain 4 highly conserved regions involved in GTP binding and hydrolysis. Rab proteins are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking; see MIM 179508.[supplied by OMIM, Apr 2006]
Chromosome	14
Cytoband	q11.2
Chromosome location (bp)	21459020 - 21476973
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000129472 (version 83.38)
Entrez gene	84932
UniProt	Q8WUD1 (UniProt - Evidence at protein level)
neXtProt	NX_Q8WUD1
Antibodypedia	RAB2B antibodies

PROTEIN BROWSER

RAB2B-001	RAB2B-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RAB2B-001 ENSP00000380869 ENST00000397762	Q8WUD1 [Direct mapping] Ras-related protein Rab-2B Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0003924 [GTPase activity] GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0005622 [intracellular] GO:0005789 [endoplasmic reticulum membrane] GO:0005886 [plasma membrane] GO:0006886 [intracellular protein transport] GO:0006913 [nucleocytoplasmic transport] GO:0007165 [signal transduction] GO:0007264 [small GTPase mediated signal transduction] GO:0015031 [protein transport] GO:0016020 [membrane] GO:0016192 [vesicle-mediated transport] GO:0032482 [Rab protein signal transduction] GO:0045921 [positive regulation of exocytosis] GO:0070062 [extracellular exosome] Show all	216 aa 24.2 kDa	No	0
RAB2B-201 ENSP00000484914 ENST00000622293	Q5HYI5 [Direct mapping] Putative uncharacterized protein DKFZp313C1541; Ras-related protein Rab-2B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0003924 [GTPase activity] GO:0005525 [GTP binding] GO:0005622 [intracellular] GO:0005789 [endoplasmic reticulum membrane] GO:0006886 [intracellular protein transport] GO:0006913 [nucleocytoplasmic transport] GO:0007165 [signal transduction] GO:0007264 [small GTPase mediated signal transduction] GO:0015031 [protein transport] GO:0016020 [membrane] GO:0032482 [Rab protein signal transduction] Show all	209 aa 23.4 kDa	No	0