Tissue expression of RAB2B - Summary - The Human Protein Atlas

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RAB2B

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	RAB2B
Gene description	RAB2B, member RAS oncogene family
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA050292
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

Cerebral cortex

Cervix, uterine

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	RAB2B (HGNC Symbol)
Synonyms	FLJ14824
Description	RAB2B, member RAS oncogene family (HGNC Symbol)
Entrez gene summary	Members of the Rab protein family are nontransforming monomeric GTP-binding proteins of the Ras superfamily that contain 4 highly conserved regions involved in GTP binding and hydrolysis. Rab proteins are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking; see MIM 179508.[supplied by OMIM, Apr 2006]
Chromosome	14
Cytoband	q11.2
Chromosome location (bp)	21459020 - 21476973
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000129472 (version 83.38)
Entrez gene	84932
UniProt	Q8WUD1 (UniProt - Evidence at protein level)
neXtProt	NX_Q8WUD1
Antibodypedia	RAB2B antibodies

PROTEIN BROWSER

RAB2B-001	RAB2B-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RAB2B-001 ENSP00000380869 ENST00000397762	Q8WUD1 [Direct mapping] Ras-related protein Rab-2B Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0003924 [GTPase activity] GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0005622 [intracellular] GO:0005789 [endoplasmic reticulum membrane] GO:0005886 [plasma membrane] GO:0006886 [intracellular protein transport] GO:0006913 [nucleocytoplasmic transport] GO:0007165 [signal transduction] GO:0007264 [small GTPase mediated signal transduction] GO:0015031 [protein transport] GO:0016020 [membrane] GO:0016192 [vesicle-mediated transport] GO:0032482 [Rab protein signal transduction] GO:0045921 [positive regulation of exocytosis] GO:0070062 [extracellular exosome] Show all	216 aa 24.2 kDa	No	0
RAB2B-201 ENSP00000484914 ENST00000622293	Q5HYI5 [Direct mapping] Putative uncharacterized protein DKFZp313C1541; Ras-related protein Rab-2B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0003924 [GTPase activity] GO:0005525 [GTP binding] GO:0005622 [intracellular] GO:0005789 [endoplasmic reticulum membrane] GO:0006886 [intracellular protein transport] GO:0006913 [nucleocytoplasmic transport] GO:0007165 [signal transduction] GO:0007264 [small GTPase mediated signal transduction] GO:0015031 [protein transport] GO:0016020 [membrane] GO:0032482 [Rab protein signal transduction] Show all	209 aa 23.4 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.