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AJUBA

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GENERAL INFORMATION

Gene name

 AJUBA

Gene description

 Ajuba LIM protein

Protein class

 Cancer-related genes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 7
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HUMAN PROTEIN ATLAS INFORMATION

Summary

 Mainly localized to the nucleus & the Golgi apparatus.

RNA cell category

 Mixed

Protein evidence

 Evidence at protein level

Main location

 Localized to the Nucleus (approved), Golgi apparatus (approved)

DATA RELIABILITY

Reliability score

 Approved based on 1 antibody.
HPA006171
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ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Mainly localized to the nucleus & the Golgi apparatus.

Main location

 Nucleus (approved), Golgi apparatus (approved)

 

 

 
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Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA006171 A-431 Nucleoplasm
Golgi apparatus
HPA006171 U-2 OS Nucleus
Golgi apparatus
Cytosol
HPA006171 U-251 MG Nucleoplasm
Golgi apparatus

GENE INFORMATION

Gene name

 AJUBA (HGNC Symbol)

Synonyms

 JUB, MGC15563

Description

 Ajuba LIM protein (HGNC Symbol)

Entrez gene summary

Chromosome

 14

Cytoband

 q11.2

Chromosome location (bp)

 22971174 - 22982642

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000129474 (version 83.38)

Entrez gene

 84962

UniProt

 Q96IF1 (UniProt - Evidence at protein level)

neXtProt

 NX_Q96IF1

Antibodypedia

 AJUBA antibodies

PROTEIN BROWSER
AJUBA-001
AJUBA-002
AJUBA-004
AJUBA-005
AJUBA-006
AJUBA-008
AJUBA-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
AJUBA-001
ENSP00000262713
ENST00000262713
Q96IF1 [Direct mapping]
LIM domain-containing protein ajuba
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000086 [G2/M transition of mitotic cell cycle]
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000278 [mitotic cell cycle]
GO:0000932 [cytoplasmic mRNA processing body]
GO:0001666 [response to hypoxia]
GO:0003682 [chromatin binding]
GO:0003714 [transcription corepressor activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005667 [transcription factor complex]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005925 [focal adhesion]
GO:0006351 [transcription, DNA-templated]
GO:0008270 [zinc ion binding]
GO:0016339 [calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules]
GO:0030027 [lamellipodium]
GO:0030032 [lamellipodium assembly]
GO:0030334 [regulation of cell migration]
GO:0031328 [positive regulation of cellular biosynthetic process]
GO:0031334 [positive regulation of protein complex assembly]
GO:0033673 [negative regulation of kinase activity]
GO:0033674 [positive regulation of kinase activity]
GO:0034613 [cellular protein localization]
GO:0035195 [gene silencing by miRNA]
GO:0035313 [wound healing, spreading of epidermal cells]
GO:0035331 [negative regulation of hippo signaling]
GO:0043087 [regulation of GTPase activity]
GO:0043123 [positive regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0043406 [positive regulation of MAP kinase activity]
GO:0045294 [alpha-catenin binding]
GO:0046474 [glycerophospholipid biosynthetic process]
GO:0048041 [focal adhesion assembly]
GO:0051015 [actin filament binding]
GO:1900037 [regulation of cellular response to hypoxia]
GO:2000637 [positive regulation of gene silencing by miRNA]
Show all
 538 aa
56.9 kDa 		No 0
AJUBA-002
ENSP00000380543
ENST00000397388
Q96IF1 [Direct mapping]
LIM domain-containing protein ajuba
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000086 [G2/M transition of mitotic cell cycle]
GO:0000278 [mitotic cell cycle]
GO:0000932 [cytoplasmic mRNA processing body]
GO:0001666 [response to hypoxia]
GO:0003714 [transcription corepressor activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0006351 [transcription, DNA-templated]
GO:0008270 [zinc ion binding]
GO:0031334 [positive regulation of protein complex assembly]
GO:0035195 [gene silencing by miRNA]
GO:0035331 [negative regulation of hippo signaling]
GO:0045294 [alpha-catenin binding]
GO:1900037 [regulation of cellular response to hypoxia]
GO:2000637 [positive regulation of gene silencing by miRNA]
Show all
 121 aa
13.8 kDa 		No 0
AJUBA-004
ENSP00000451772
ENST00000553736
H0YJL9 [Direct mapping]
LIM domain-containing protein ajuba
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
 143 aa
14.8 kDa 		No 0
AJUBA-005
ENSP00000451649
ENST00000556731
G3V481 [Direct mapping]
LIM domain-containing protein ajuba
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0008270 [zinc ion binding]
Show all
 80 aa
9.1 kDa 		No 0
AJUBA-006
ENSP00000452325
ENST00000553911
G3V5F5 [Direct mapping]
LIM domain-containing protein ajuba
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0008270 [zinc ion binding]
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 65 aa
7.2 kDa 		No 0
AJUBA-008
ENSP00000452369
ENST00000553592
G3V481 [Direct mapping]
LIM domain-containing protein ajuba
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0008270 [zinc ion binding]
Show all
 80 aa
9.1 kDa 		No 0
AJUBA-201
ENSP00000354491
ENST00000361265
Q96IF1 [Direct mapping]
LIM domain-containing protein ajuba
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000086 [G2/M transition of mitotic cell cycle]
GO:0000278 [mitotic cell cycle]
GO:0000932 [cytoplasmic mRNA processing body]
GO:0001666 [response to hypoxia]
GO:0003714 [transcription corepressor activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0006351 [transcription, DNA-templated]
GO:0008270 [zinc ion binding]
GO:0031334 [positive regulation of protein complex assembly]
GO:0035195 [gene silencing by miRNA]
GO:0035331 [negative regulation of hippo signaling]
GO:0045294 [alpha-catenin binding]
GO:1900037 [regulation of cellular response to hypoxia]
GO:2000637 [positive regulation of gene silencing by miRNA]
Show all
 538 aa
56.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.