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EAPP

CANCER ATLAS

Gene description

 E2F-associated phosphoprotein

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA002916

GENE INFORMATION

Gene name

 EAPP (HGNC Symbol)

Synonyms

 BM036, C14orf11, FLJ20578

Description

 E2F-associated phosphoprotein (HGNC Symbol)

Entrez gene summary

 This gene encodes a phosphoprotein that interacts with several members of the E2F family of proteins. The protein localizes to the nucleus, and is present throughout the cell cycle except during mitosis. It functions to modulate E2F-regulated transcription and stimulate proliferation. [provided by RefSeq, Jul 2008]

Chromosome

 14

Cytoband

 q13.1

Chromosome location (bp)

 34515929 - 34539711

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000129518 (version 83.38)

Entrez gene

 55837

UniProt

 Q56P03 (UniProt - Evidence at protein level)

neXtProt

 NX_Q56P03

Antibodypedia

 EAPP antibodies

PROTEIN BROWSER
EAPP-001
EAPP-004
EAPP-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
EAPP-001
ENSP00000250454
ENST00000250454
Q56P03 [Direct mapping]
E2F-associated phosphoprotein
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005794 [Golgi apparatus]
GO:0008284 [positive regulation of cell proliferation]
GO:0032968 [positive regulation of transcription elongation from RNA polymerase II promoter]
GO:0034244 [negative regulation of transcription elongation from RNA polymerase II promoter]
Show all
 285 aa
32.8 kDa 		No 0
EAPP-004
ENSP00000450908
ENST00000554792
G3V2W9 [Direct mapping]
E2F-associated phosphoprotein
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005794 [Golgi apparatus]
Show all
 205 aa
23.5 kDa 		No 0
EAPP-201
ENSP00000483122
ENST00000618169
A0A087X060 [Direct mapping]
E2F-associated phosphoprotein
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 231 aa
26.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.