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EAPP

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GENERAL INFORMATION

Gene name

 EAPP

Gene description

 E2F-associated phosphoprotein

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

Summary

 Mainly localized to the Golgi apparatus. In addition localized to the nucleus & cytosol.

RNA cell category

 Expressed in all

Protein evidence

 Evidence at protein level

Main location

 Localized to the Golgi apparatus (approved)

Additional location

 In addition localized to the Nucleus (supported), Cytosol (supported)

DATA RELIABILITY

Reliability score

 Approved based on 1 antibody.
HPA002916
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ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Mainly localized to the Golgi apparatus. In addition localized to the nucleus & cytosol.

Main location

 Golgi apparatus (approved)

Additional location

 Nucleus (supported), Cytosol (supported)

 

 

 
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Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA002916 A-431 Nucleus
Golgi apparatus
Cytosol
HPA002916 U-2 OS Golgi apparatus
Cytosol
HPA002916 U-251 MG Nucleoplasm
Golgi apparatus

GENE INFORMATION

Gene name

 EAPP (HGNC Symbol)

Synonyms

 BM036, C14orf11, FLJ20578

Description

 E2F-associated phosphoprotein (HGNC Symbol)

Entrez gene summary

 This gene encodes a phosphoprotein that interacts with several members of the E2F family of proteins. The protein localizes to the nucleus, and is present throughout the cell cycle except during mitosis. It functions to modulate E2F-regulated transcription and stimulate proliferation. [provided by RefSeq, Jul 2008]

Chromosome

 14

Cytoband

 q13.1

Chromosome location (bp)

 34515929 - 34539711

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000129518 (version 83.38)

Entrez gene

 55837

UniProt

 Q56P03 (UniProt - Evidence at protein level)

neXtProt

 NX_Q56P03

Antibodypedia

 EAPP antibodies

PROTEIN BROWSER
EAPP-001
EAPP-004
EAPP-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
EAPP-001
ENSP00000250454
ENST00000250454
Q56P03 [Direct mapping]
E2F-associated phosphoprotein
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005794 [Golgi apparatus]
GO:0008284 [positive regulation of cell proliferation]
GO:0032968 [positive regulation of transcription elongation from RNA polymerase II promoter]
GO:0034244 [negative regulation of transcription elongation from RNA polymerase II promoter]
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 285 aa
32.8 kDa 		No 0
EAPP-004
ENSP00000450908
ENST00000554792
G3V2W9 [Direct mapping]
E2F-associated phosphoprotein
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005794 [Golgi apparatus]
Show all
 205 aa
23.5 kDa 		No 0
EAPP-201
ENSP00000483122
ENST00000618169
A0A087X060 [Direct mapping]
E2F-associated phosphoprotein
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 231 aa
26.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.