Cell atlas - HBZ - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

HBZ

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	HBZ
Gene description	Hemoglobin, zeta
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enriched (K-562)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enriched (K-562) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	HBZ (HGNC Symbol)
Synonyms	HBZ-T1, HBZ1
Description	Hemoglobin, zeta (HGNC Symbol)
Entrez gene summary	Zeta-globin is an alpha-like hemoglobin. The zeta-globin polypeptide is synthesized in the yolk sac of the early embryo, while alpha-globin is produced throughout fetal and adult life. The zeta-globin gene is a member of the human alpha-globin gene cluster that includes five functional genes and two pseudogenes. The order of genes is: 5' - zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 -alpha-1 - theta1 - 3'. [provided by RefSeq, Nov 2009]
Chromosome	16
Cytoband	p13.3
Chromosome location (bp)	152687 - 154503
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000130656 (version 83.38)
Entrez gene	3050
UniProt	P02008 (UniProt - Evidence at protein level)
neXtProt	NX_P02008
Antibodypedia	HBZ antibodies

PROTEIN BROWSER

HBZ-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
HBZ-001 ENSP00000252951 ENST00000252951	P02008 [Direct mapping] Hemoglobin subunit zeta Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0005344 [oxygen transporter activity] GO:0005506 [iron ion binding] GO:0005515 [protein binding] GO:0005833 [hemoglobin complex] GO:0015671 [oxygen transport] GO:0019825 [oxygen binding] GO:0020037 [heme binding] GO:0043249 [erythrocyte maturation] GO:0070062 [extracellular exosome] Show all	142 aa 15.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.