Many carcinoids, hepatocellular carcinomas and prostate cancers along with a few colorectal, ovarian and pancreatic cancers displayed moderate cytoplasmic positivity. Cases of ductal breast carcinomas were strongly stained. Remaining cancer cells were in general weakly stained or negative.
Most cancers exhibited moderate nuclear positivity. Rarely prostate cancers showed strong positivity. Majority of testis and cervical cancers were weakly stained or negative.
SLC7A10 (HGNC Symbol)
Solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 (HGNC Symbol)
Entrez gene summary
SLC7A10, in association with 4F2HC (SLC3A2; MIM 158070), mediates high-affinity transport of D-serine and several other neutral amino acids (Nakauchi et al., 2000 [PubMed 10863037]).[supplied by OMIM, Mar 2008]