Expression of SLC7A10 in cancer - Summary

CANCER ATLAS

Gene description

Solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10

Protein class

Predicted membrane proteins, Transporters

Protein evidence

Evidence at transcript level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA041884	HPA057036

GENE INFORMATION
Gene name	SLC7A10 (HGNC Symbol)
Synonyms	asc-1
Description	Solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 (HGNC Symbol)
Entrez gene summary	SLC7A10, in association with 4F2HC (SLC3A2; MIM 158070), mediates high-affinity transport of D-serine and several other neutral amino acids (Nakauchi et al., 2000 [PubMed 10863037]).[supplied by OMIM, Mar 2008]
Chromosome	19
Cytoband	q13.11
Chromosome location (bp)	33208664 - 33225850
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000130876 (version 83.38)
Entrez gene	56301
UniProt	Q9NS82 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9NS82
Antibodypedia	SLC7A10 antibodies

PROTEIN BROWSER

SLC7A10-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC7A10-001 ENSP00000253188 ENST00000253188	Q9NS82 [Direct mapping] Asc-type amino acid transporter 1 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Show all	GO:0003333 [amino acid transmembrane transport] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006811 [ion transport] GO:0006865 [amino acid transport] GO:0007596 [blood coagulation] GO:0015171 [amino acid transmembrane transporter activity] GO:0015175 [neutral amino acid transmembrane transporter activity] GO:0015194 [L-serine transmembrane transporter activity] GO:0015297 [antiporter activity] GO:0015804 [neutral amino acid transport] GO:0015825 [L-serine transport] GO:0016020 [membrane] GO:0030425 [dendrite] GO:0042941 [D-alanine transport] GO:0042942 [D-serine transport] GO:0042945 [D-serine transmembrane transporter activity] GO:0050900 [leukocyte migration] GO:0055085 [transmembrane transport] Show all	523 aa 56.8 kDa	No	>9