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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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SLC7A10
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TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

SLC7A10

Gene description

Solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10

Protein class

Predicted membrane proteins
Transporters

Predicted localization

Membrane

Number of transcripts

1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Group enriched (adipose tissue, cerebral cortex)
GTEx:Tissue enhanced (adipose tissue, caudate, breast)
FANTOM5:Tissue enhanced (breast, caudate, retina)

Protein evidence

Evidence at transcript level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY

Data reliability
description

RNA-based expert annotation gave inconclusive results. Pending external verification.

Reliability score

Uncertain based on 2 antibodies.
HPA041884 , HPA057036
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
N/A
Cerebral cortex
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Thyroid gland
N/A
Parathyroid gland
N/A
Adrenal gland
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Bone marrow
N/A
Lymph node
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Heart muscle
N/A
Skeletal muscle
N/A
Smooth muscle
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Gallbladder
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Salivary gland
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Small intestine
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
Prostate
N/A
Seminal vesicle
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
Endometrium
N/A
Fallopian tube
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Adipose tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Pancreas

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW

RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (adipose tissue, cerebral cortex)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (adipose tissue, caudate, breast)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (breast, caudate, retina)

GENE INFORMATION

Gene name

SLC7A10 (HGNC Symbol)

Synonyms

asc-1

Description

Solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 (HGNC Symbol)

Entrez gene summary

SLC7A10, in association with 4F2HC (SLC3A2; MIM 158070), mediates high-affinity transport of D-serine and several other neutral amino acids (Nakauchi et al., 2000 [PubMed 10863037]).[supplied by OMIM, Mar 2008]

Chromosome

19

Cytoband

q13.11

Chromosome location (bp)

33208664 - 33225850

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000130876 (version 83.38)

Entrez gene

56301

UniProt

Q9NS82 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9NS82

Antibodypedia

SLC7A10 antibodies

PROTEIN BROWSER

SLC7A10-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLC7A10-001
ENSP00000253188
ENST00000253188
Q9NS82 [Direct mapping]
Asc-type amino acid transporter 1
Show all
Transporters
   Electrochemical Potential-driven transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   >9TM proteins predicted by MDM
Show all
GO:0003333 [amino acid transmembrane transport]
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006811 [ion transport]
GO:0006865 [amino acid transport]
GO:0007596 [blood coagulation]
GO:0015171 [amino acid transmembrane transporter activity]
GO:0015175 [neutral amino acid transmembrane transporter activity]
GO:0015194 [L-serine transmembrane transporter activity]
GO:0015297 [antiporter activity]
GO:0015804 [neutral amino acid transport]
GO:0015825 [L-serine transport]
GO:0016020 [membrane]
GO:0030425 [dendrite]
GO:0042941 [D-alanine transport]
GO:0042942 [D-serine transport]
GO:0042945 [D-serine transmembrane transporter activity]
GO:0050900 [leukocyte migration]
GO:0055085 [transmembrane transport]
Show all
523 aa
56.8 kDa
No >9

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