Tissue expression of SLC7A10 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	SLC7A10
Gene description	Solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10
Protein class	Predicted membrane proteins Transporters
Predicted localization	Membrane
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Group enriched (adipose tissue, cerebral cortex)
GTEx:	Tissue enhanced (adipose tissue, caudate, breast)
FANTOM5:	Tissue enhanced (breast, caudate, retina)

Protein evidence

Evidence at transcript level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 2 antibodies. HPA041884 , HPA057036
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Group enriched (adipose tissue, cerebral cortex)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (adipose tissue, caudate, breast)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (breast, caudate, retina)

GENE INFORMATION
Gene name	SLC7A10 (HGNC Symbol)
Synonyms	asc-1
Description	Solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 (HGNC Symbol)
Entrez gene summary	SLC7A10, in association with 4F2HC (SLC3A2; MIM 158070), mediates high-affinity transport of D-serine and several other neutral amino acids (Nakauchi et al., 2000 [PubMed 10863037]).[supplied by OMIM, Mar 2008]
Chromosome	19
Cytoband	q13.11
Chromosome location (bp)	33208664 - 33225850
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000130876 (version 83.38)
Entrez gene	56301
UniProt	Q9NS82 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9NS82
Antibodypedia	SLC7A10 antibodies

PROTEIN BROWSER

SLC7A10-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC7A10-001 ENSP00000253188 ENST00000253188	Q9NS82 [Direct mapping] Asc-type amino acid transporter 1 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Show all	GO:0003333 [amino acid transmembrane transport] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006811 [ion transport] GO:0006865 [amino acid transport] GO:0007596 [blood coagulation] GO:0015171 [amino acid transmembrane transporter activity] GO:0015175 [neutral amino acid transmembrane transporter activity] GO:0015194 [L-serine transmembrane transporter activity] GO:0015297 [antiporter activity] GO:0015804 [neutral amino acid transport] GO:0015825 [L-serine transport] GO:0016020 [membrane] GO:0030425 [dendrite] GO:0042941 [D-alanine transport] GO:0042942 [D-serine transport] GO:0042945 [D-serine transmembrane transporter activity] GO:0050900 [leukocyte migration] GO:0055085 [transmembrane transport] Show all	523 aa 56.8 kDa	No	>9