Expression of FBP2 in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Fructose-1,6-bisphosphatase 2

Protein class

Enzymes, Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA012513

GENE INFORMATION
Gene name	FBP2
Synonyms
Description	Fructose-1,6-bisphosphatase 2 (HGNC Symbol)
Entrez gene summary	This gene encodes a gluconeogenesis regulatory enzyme which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. [provided by RefSeq, Jul 2008]
Chromosome	9
Cytoband	q22.32
Chromosome location (bp)	94558720 - 94593793
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000130957 (version 83.38)
Entrez gene	8789
UniProt	O00757 (UniProt - Evidence at protein level)
neXtProt	NX_O00757
Antibodypedia	FBP2 antibodies

PROTEIN BROWSER

FBP2-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FBP2-001 ENSP00000364486 ENST00000375337	O00757 [Direct mapping] Fructose-1,6-bisphosphatase isozyme 2 Show all	Enzymes ENZYME proteins Hydrolases SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005829 [cytosol] GO:0005975 [carbohydrate metabolic process] GO:0006000 [fructose metabolic process] GO:0006006 [glucose metabolic process] GO:0006094 [gluconeogenesis] GO:0016311 [dephosphorylation] GO:0030018 [Z disc] GO:0030054 [cell junction] GO:0042132 [fructose 1,6-bisphosphate 1-phosphatase activity] GO:0042578 [phosphoric ester hydrolase activity] GO:0044281 [small molecule metabolic process] GO:0046872 [metal ion binding] GO:0070062 [extracellular exosome] Show all	339 aa 36.7 kDa	No	0