Cell atlas - POPDC3 - The Human Protein Atlas

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POPDC3

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Nucleoli

Human cell
	Cytosol
	Nucleoli

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GENERAL INFORMATION
Gene name	POPDC3
Gene description	Popeye domain containing 3
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleoli & cytosol.
RNA cell category	Cell line enhanced (RH-30)
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoli (approved), Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA012514
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (RH-30) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleoli & cytosol.

Main location

Nucleoli (approved), Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA012514	A-431	Nucleoli
	HPA012514	A-431	Cytosol
	HPA012514	U-2 OS	Nucleoli
	HPA012514	U-2 OS	Cytosol
	HPA012514	U-251 MG	Nucleoli
	HPA012514	U-251 MG	Cytosol

GENE INFORMATION
Gene name	POPDC3 (HGNC Symbol)
Synonyms	bA355M14.1, MGC22671, POP3
Description	Popeye domain containing 3 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the POP family of proteins containing three putative transmembrane domains. This gene is expressed in cardiac and skeletal muscle and may play an important role in these tissues during development. Alternatively spliced transcript variants have been found. [provided by RefSeq, Nov 2008]
Chromosome	6
Cytoband	q21
Chromosome location (bp)	105158280 - 105179995
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000132429 (version 83.38)
Entrez gene	64208
UniProt	Q9HBV1 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9HBV1
Antibodypedia	POPDC3 antibodies

PROTEIN BROWSER

POPDC3-001	POPDC3-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
POPDC3-001 ENSP00000254765 ENST00000254765	Q9HBV1 [Direct mapping] Popeye domain-containing protein 3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0003674 [molecular_function] GO:0008150 [biological_process] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0042391 [regulation of membrane potential] Show all	291 aa 33.9 kDa	No	2
POPDC3-004 ENSP00000414409 ENST00000429112	Q5T554 [Direct mapping] Popeye domain-containing protein 3 Show all	Predicted intracellular proteins Show all	GO:0016020 [membrane] Show all	101 aa 12.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.