Tissue expression of POPDC3 - Summary - The Human Protein Atlas

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POPDC3

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	POPDC3
Gene description	Popeye domain containing 3
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Group enriched (skeletal muscle, heart muscle, testis, cerebral cortex)
GTEx:	Tissue enhanced (skeletal muscle)
FANTOM5:	Group enriched (skeletal muscle, heart muscle)

Protein evidence

Evidence at protein level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA012514
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Group enriched (skeletal muscle, heart muscle, testis, cerebral cortex)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (skeletal muscle)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Group enriched (skeletal muscle, heart muscle)

GENE INFORMATION
Gene name	POPDC3 (HGNC Symbol)
Synonyms	bA355M14.1, MGC22671, POP3
Description	Popeye domain containing 3 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the POP family of proteins containing three putative transmembrane domains. This gene is expressed in cardiac and skeletal muscle and may play an important role in these tissues during development. Alternatively spliced transcript variants have been found. [provided by RefSeq, Nov 2008]
Chromosome	6
Cytoband	q21
Chromosome location (bp)	105158280 - 105179995
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000132429 (version 83.38)
Entrez gene	64208
UniProt	Q9HBV1 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9HBV1
Antibodypedia	POPDC3 antibodies

PROTEIN BROWSER

POPDC3-001	POPDC3-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
POPDC3-001 ENSP00000254765 ENST00000254765	Q9HBV1 [Direct mapping] Popeye domain-containing protein 3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0003674 [molecular_function] GO:0008150 [biological_process] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0042391 [regulation of membrane potential] Show all	291 aa 33.9 kDa	No	2
POPDC3-004 ENSP00000414409 ENST00000429112	Q5T554 [Direct mapping] Popeye domain-containing protein 3 Show all	Predicted intracellular proteins Show all	GO:0016020 [membrane] Show all	101 aa 12.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.