Expression of HSPA12B in cancer - Summary

CANCER ATLAS

Gene description

Heat shock 70kD protein 12B

Protein class

Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Endometrial cancer

STAINING SUMMARY

HPA013659	HPA015639

GENE INFORMATION
Gene name	HSPA12B (HGNC Symbol)
Synonyms	C20orf60, dJ1009E24.2
Description	Heat shock 70kD protein 12B (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene contains an atypical heat shock protein 70 (Hsp70) ATPase domain and is therefore a distant member of the mammalian Hsp70 family. This gene may be involved in susceptibility to atherosclerosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2010]
Chromosome	20
Cytoband	p13
Chromosome location (bp)	3732667 - 3753111
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000132622 (version 83.38)
Entrez gene	116835
UniProt	Q96MM6 (UniProt - Evidence at protein level)
neXtProt	NX_Q96MM6
Antibodypedia	HSPA12B antibodies

PROTEIN BROWSER

HSPA12B-001	HSPA12B-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
HSPA12B-001 ENSP00000254963 ENST00000254963	Q96MM6 [Direct mapping] Heat shock 70 kDa protein 12B Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005524 [ATP binding] Show all	686 aa 75.7 kDa	No	0
HSPA12B-002 ENSP00000382608 ENST00000399701	Q5JX83 [Direct mapping] Heat shock 70 kDa protein 12B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		600 aa 66.8 kDa	No	0