Tissue expression of HSPA12B - Summary - The Human Protein Atlas

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HSPA12B

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	HSPA12B
Gene description	Heat shock 70kD protein 12B
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Mixed
GTEx:	Expressed in all
FANTOM5:	Mixed

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in most tissues.

DATA RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 2 antibodies. HPA013659 , HPA015639
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Mixed
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Mixed

GENE INFORMATION
Gene name	HSPA12B (HGNC Symbol)
Synonyms	C20orf60, dJ1009E24.2
Description	Heat shock 70kD protein 12B (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene contains an atypical heat shock protein 70 (Hsp70) ATPase domain and is therefore a distant member of the mammalian Hsp70 family. This gene may be involved in susceptibility to atherosclerosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2010]
Chromosome	20
Cytoband	p13
Chromosome location (bp)	3732667 - 3753111
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000132622 (version 83.38)
Entrez gene	116835
UniProt	Q96MM6 (UniProt - Evidence at protein level)
neXtProt	NX_Q96MM6
Antibodypedia	HSPA12B antibodies

PROTEIN BROWSER

HSPA12B-001	HSPA12B-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
HSPA12B-001 ENSP00000254963 ENST00000254963	Q96MM6 [Direct mapping] Heat shock 70 kDa protein 12B Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005524 [ATP binding] Show all	686 aa 75.7 kDa	No	0
HSPA12B-002 ENSP00000382608 ENST00000399701	Q5JX83 [Direct mapping] Heat shock 70 kDa protein 12B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		600 aa 66.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.