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This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Q9UIF7 [Direct mapping] A/G-specific adenine DNA glycosylase E5KP27 [Target identity:100%; Query identity:100%] A/G-specific adenine DNA glycosylase; MutY homolog (E. coli), isoform CRA_d
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Predicted intracellular proteins Cancer-related genes Candidate cancer biomarkers COSMIC somatic mutations in cancer genes COSMIC Missense Mutations COSMIC Germline Mutations Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Q9UIF7 [Direct mapping] A/G-specific adenine DNA glycosylase E5KP26 [Target identity:100%; Query identity:100%] A/G-specific adenine DNA glycosylase; MutY homolog (E. coli), isoform CRA_e
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Predicted intracellular proteins Cancer-related genes Candidate cancer biomarkers COSMIC somatic mutations in cancer genes COSMIC Missense Mutations COSMIC Germline Mutations Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Q9UIF7 [Direct mapping] A/G-specific adenine DNA glycosylase
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Predicted intracellular proteins Cancer-related genes Candidate cancer biomarkers COSMIC somatic mutations in cancer genes COSMIC Missense Mutations COSMIC Germline Mutations Disease related genes Protein evidence (Ezkurdia et al 2014)
Q9UIF7 [Direct mapping] A/G-specific adenine DNA glycosylase
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Predicted intracellular proteins Cancer-related genes Candidate cancer biomarkers COSMIC somatic mutations in cancer genes COSMIC Missense Mutations COSMIC Germline Mutations Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Q9UIF7 [Direct mapping] A/G-specific adenine DNA glycosylase
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Predicted intracellular proteins Cancer-related genes Candidate cancer biomarkers COSMIC somatic mutations in cancer genes COSMIC Missense Mutations COSMIC Germline Mutations Disease related genes Protein evidence (Ezkurdia et al 2014)
Q9UIF7 [Direct mapping] A/G-specific adenine DNA glycosylase E5KP28 [Target identity:100%; Query identity:100%] A/G-specific adenine DNA glycosylase; MutY homolog (E. coli), isoform CRA_b
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Predicted intracellular proteins Cancer-related genes Candidate cancer biomarkers COSMIC somatic mutations in cancer genes COSMIC Missense Mutations COSMIC Germline Mutations Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Q9UIF7 [Direct mapping] A/G-specific adenine DNA glycosylase
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Predicted intracellular proteins Cancer-related genes Candidate cancer biomarkers COSMIC somatic mutations in cancer genes COSMIC Missense Mutations COSMIC Germline Mutations Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Q9UIF7 [Direct mapping] A/G-specific adenine DNA glycosylase
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Predicted intracellular proteins Cancer-related genes Candidate cancer biomarkers COSMIC somatic mutations in cancer genes COSMIC Missense Mutations COSMIC Germline Mutations Disease related genes Protein evidence (Ezkurdia et al 2014)
Q5T418 [Direct mapping] A/G-specific adenine DNA glycosylase
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Predicted intracellular proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Missense Mutations COSMIC Germline Mutations Protein evidence (Ezkurdia et al 2014)
Q5T413 [Direct mapping] A/G-specific adenine DNA glycosylase
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Predicted intracellular proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Missense Mutations COSMIC Germline Mutations Protein evidence (Ezkurdia et al 2014)
E9PP34 [Direct mapping] A/G-specific adenine DNA glycosylase
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Predicted intracellular proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Missense Mutations COSMIC Germline Mutations Protein evidence (Ezkurdia et al 2014)
E9PNY0 [Direct mapping] A/G-specific adenine DNA glycosylase
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Predicted intracellular proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Missense Mutations COSMIC Germline Mutations Protein evidence (Ezkurdia et al 2014)
E9PM53 [Direct mapping] A/G-specific adenine DNA glycosylase
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Predicted intracellular proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Missense Mutations COSMIC Germline Mutations Protein evidence (Ezkurdia et al 2014)
E9PNY0 [Direct mapping] A/G-specific adenine DNA glycosylase
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Predicted intracellular proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Missense Mutations COSMIC Germline Mutations Protein evidence (Ezkurdia et al 2014)
E9PLT4 [Direct mapping] A/G-specific adenine DNA glycosylase
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Predicted intracellular proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Missense Mutations COSMIC Germline Mutations Protein evidence (Ezkurdia et al 2014)
H0YCY5 [Direct mapping] A/G-specific adenine DNA glycosylase
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Predicted intracellular proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Missense Mutations COSMIC Germline Mutations Protein evidence (Ezkurdia et al 2014)
E5KP25 [Direct mapping] A/G-specific adenine DNA glycosylase
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Predicted intracellular proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Missense Mutations COSMIC Germline Mutations Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
