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A majority of malignant cells exhibited weak to moderate cytoplasmic positivity. A few cases of thyroid and renal cancers were strongly stained. Testicular and squamous cell carcinomas in addition showed nuclear positivity in several cases as well as malignant lymphomas. Most cases of malignant gliomas, lymphomas and skin cancers were negative.
Malignant tissues exhibited weak to moderate cytoplasmic positivity. Several cases of non-Hodgkin's lymphomas were negative.
GENE INFORMATION
Gene name
RNF17 (HGNC Symbol)
Synonyms
FLJ11045, Mmip-2, SPATA23, TDRD4
Description
Ring finger protein 17 (HGNC Symbol)
Entrez gene summary
This gene is similar to a mouse gene that encodes a testis-specific protein containing a RING finger domain. Alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, May 2010]
