Expression of COG6 in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Component of oligomeric golgi complex 6

Protein class

Disease related genes, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA040410	HPA040441

GENE INFORMATION
Gene name	COG6 (HGNC Symbol)
Synonyms	COD2, KIAA1134
Description	Component of oligomeric golgi complex 6 (HGNC Symbol)
Entrez gene summary	This gene encodes a subunit of the conserved oligomeric Golgi complex that is required for maintaining normal structure and activity of the Golgi apparatus. The encoded protein is organized with conserved oligomeric Golgi complex components 5, 7 and 8 into a sub-complex referred to as lobe B. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Feb 2009]
Chromosome	13
Cytoband	q14.11
Chromosome location (bp)	39655627 - 39791665
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000133103 (version 83.38)
Entrez gene	57511
UniProt	Q9Y2V7 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y2V7
Antibodypedia	COG6 antibodies

PROTEIN BROWSER

COG6-001	COG6-002	COG6-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
COG6-001 ENSP00000403733 ENST00000416691	Q9Y2V7 [Direct mapping] Conserved oligomeric Golgi complex subunit 6 Show all	Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0006891 [intra-Golgi vesicle-mediated transport] GO:0015031 [protein transport] GO:0017119 [Golgi transport complex] GO:0070085 [glycosylation] Show all	615 aa 68.4 kDa	No	0
COG6-002 ENSP00000397441 ENST00000455146	Q9Y2V7 [Direct mapping] Conserved oligomeric Golgi complex subunit 6 A0A024RDW5 [Target identity:100%; Query identity:100%] Component of oligomeric golgi complex 6, isoform CRA_b Show all	Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0006891 [intra-Golgi vesicle-mediated transport] GO:0015031 [protein transport] GO:0017119 [Golgi transport complex] GO:0070085 [glycosylation] Show all	657 aa 73.3 kDa	No	0
COG6-201 ENSP00000486051 ENST00000630730	F5GX76 [Direct mapping] Conserved oligomeric Golgi complex subunit 6 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005622 [intracellular] GO:0006891 [intra-Golgi vesicle-mediated transport] Show all	61 aa 6.3 kDa	No	0