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COG6

GENERAL INFORMATION

Gene name

 COG6

Gene description

 Component of oligomeric golgi complex 6

Protein class

 Disease related genes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 general cytoplasmic expression, including occasional nuclear expression.

DATA RELIABILITY

Data reliability
description

 Pending external verification.

Reliability score

 Uncertain based on 2 antibodies.
HPA040410 , HPA040441
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 COG6 (HGNC Symbol)

Synonyms

 COD2, KIAA1134

Description

 Component of oligomeric golgi complex 6 (HGNC Symbol)

Entrez gene summary

 This gene encodes a subunit of the conserved oligomeric Golgi complex that is required for maintaining normal structure and activity of the Golgi apparatus. The encoded protein is organized with conserved oligomeric Golgi complex components 5, 7 and 8 into a sub-complex referred to as lobe B. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Feb 2009]

Chromosome

 13

Cytoband

 q14.11

Chromosome location (bp)

 39655627 - 39791665

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000133103 (version 83.38)

Entrez gene

 57511

UniProt

 Q9Y2V7 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9Y2V7

Antibodypedia

 COG6 antibodies

PROTEIN BROWSER
COG6-001
COG6-002
COG6-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
COG6-001
ENSP00000403733
ENST00000416691
Q9Y2V7 [Direct mapping]
Conserved oligomeric Golgi complex subunit 6
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Predicted intracellular proteins
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0006891 [intra-Golgi vesicle-mediated transport]
GO:0015031 [protein transport]
GO:0017119 [Golgi transport complex]
GO:0070085 [glycosylation]
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 615 aa
68.4 kDa 		No 0
COG6-002
ENSP00000397441
ENST00000455146
Q9Y2V7 [Direct mapping]
Conserved oligomeric Golgi complex subunit 6
A0A024RDW5 [Target identity:100%; Query identity:100%]
Component of oligomeric golgi complex 6, isoform CRA_b
Show all
Predicted intracellular proteins
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0006891 [intra-Golgi vesicle-mediated transport]
GO:0015031 [protein transport]
GO:0017119 [Golgi transport complex]
GO:0070085 [glycosylation]
Show all
 657 aa
73.3 kDa 		No 0
COG6-201
ENSP00000486051
ENST00000630730
F5GX76 [Direct mapping]
Conserved oligomeric Golgi complex subunit 6
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005622 [intracellular]
GO:0006891 [intra-Golgi vesicle-mediated transport]
Show all
 61 aa
6.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.